Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| Psychrophilin E, a new cyclotripeptide, from co-fermentation of two marine alga-derived fungi of the genus Aspergillus | |
Ebada, Sherif S.1,4; Fischer, Thomas1; Hamacher, Alexandra2; Du, Feng-Yu3; Roth, Yoen Ok1; Kassack, Matthias U.2; Wang, Bin-Gui3 ; Roth, Eckhard H.1; Ebada, SS (reprint author), BIOMAR, Merowingerpl 1a, D-40225 Dusseldorf, Germany.
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| 2014-06-03 | |
| 发表期刊 | NATURAL PRODUCT RESEARCH
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| 卷号 | 28期号:11页码:776-781 |
| 文章类型 | Article |
| 摘要 | Chemical investigation of the mycelial extract of a mixed culture of two marine alga-derived fungal strains of the genus Aspergillus has yielded one new cyclotripeptide, psychrophilin E (1), the recently reported oxepin-containing alkaloids, protuboxepin A (2) and oxepinamide E (3), together with three other polyketide derivatives (4-6). The chemical structure and relative and absolute configurations of psychrophilin E (1) were unambiguously established based on HRMS, 1D, 2D NMR and chiral-phase HPLC analysis of its hydrolysate. All the isolated compounds were assessed for their anti-proliferative activity against four different human cancer cell lines and some of them revealed selective activities. |
| 关键词 | Aspergillus Co-fermentation Marine-derived Fungi Anti-proliferative |
| 学科领域 | Chemistry ; Pharmacology & Pharmacy |
| DOI | 10.1080/14786419.2014.880911 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000335942400009 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/24152 |
| 专题 | 实验海洋生物学重点实验室 |
| 通讯作者 | Ebada, SS (reprint author), BIOMAR, Merowingerpl 1a, D-40225 Dusseldorf, Germany. |
| 作者单位 | 1.BIOMAR, D-40225 Dusseldorf, Germany 2.Univ Dusseldorf, Inst Pharmazeut & Med Chem, D-40225 Dusseldorf, Germany 3.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 4.Ain Shams Univ, Dept Pharmacognosy & Phytochem, Fac Pharm, Cairo 11566, Egypt |
| 推荐引用方式 GB/T 7714 | Ebada, Sherif S.,Fischer, Thomas,Hamacher, Alexandra,et al. Psychrophilin E, a new cyclotripeptide, from co-fermentation of two marine alga-derived fungi of the genus Aspergillus[J]. NATURAL PRODUCT RESEARCH,2014,28(11):776-781. |
| APA | Ebada, Sherif S..,Fischer, Thomas.,Hamacher, Alexandra.,Du, Feng-Yu.,Roth, Yoen Ok.,...&Ebada, SS .(2014).Psychrophilin E, a new cyclotripeptide, from co-fermentation of two marine alga-derived fungi of the genus Aspergillus.NATURAL PRODUCT RESEARCH,28(11),776-781. |
| MLA | Ebada, Sherif S.,et al."Psychrophilin E, a new cyclotripeptide, from co-fermentation of two marine alga-derived fungi of the genus Aspergillus".NATURAL PRODUCT RESEARCH 28.11(2014):776-781. |
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