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题名: Prenylated Indole Alkaloid Derivatives from Marine Sediment-Derived Fungus Penicillium paneum SD-44
作者: Li, Chun-Shun; Li, Xiao-Ming; An, Chun-Yan; Wang, BinGui(王斌贵)
刊名: HELVETICA CHIMICA ACTA
出版日期: 2014-10-01
卷号: 97, 期号:10, 页码:1440-1444
关键词: Penicillium paneum ; -Carbolines ; Alkaloids ; Indole alkaloids
学科分类: Chemistry
DOI: 10.1002/hlca.201400035
通讯作者: Wang, BG (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China.
文章类型: Article
英文摘要: Three new prenylated indole alkaloids, including two -carbolines, penipalines A and B (1 and 2, resp.), and one indole carbaldehyde derivative, penipaline C (3), as well as two known indole derived analogs, 4 and 5, were isolated from the deep-sea-sediment derived fungus Penicillium paneum SD-44 cultured in a 500-l bioreactor. The structures of the new compounds were determined on the basis of 1D- and 2D-NMR spectroscopy, as well as by high-resolution mass spectrometry. The new compounds 2 and 3 showed potent cytotoxic activities against A-549 and HCT-116 cell lines.
收录类别: SCI ; IC
语种: 英语
WOS记录号: WOS:000344180200015
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.qdio.ac.cn/handle/337002/24149
Appears in Collections:实验海洋生物学重点实验室_期刊论文

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作者单位: Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
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