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| Brocazines A-F, Cytotoxic Bisthiodiketopiperazine Derivatives from Penicillium brocae MA-231, an Endophytic Fungus Derived from the Marine Mangrove Plant Avicennia marina | |
Meng, Ling-Hong1,2 ; Li, Xiao-Ming1; Lv, Cui-Ting3; Huang, Cai-Guo3; Wang, Bin-Gui1; Huang, CG (reprint author), Second Mil Med Univ, Dept Biochem & Mol Biol, Xiangyin Rd 800, Shanghai 200433, Peoples R China.
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| 2014-08-01 | |
| 发表期刊 | JOURNAL OF NATURAL PRODUCTS
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| 卷号 | 77期号:8页码:1921-1927 |
| 文章类型 | Article |
| 摘要 | Six new disulfide-bridged diketopiperazine derivatives, brocazines A-F (1-6), along with one known analogue (7), were isolated and identified from the cytotoxic extract of Penicillium brocae MA-231, a fungus obtained from the fresh tissue of the marine mangrove plant Avicennia marina. The structures of these compounds were established on the basis of detailed interpretation of NMR and mass spectroscopic data. X-ray crystallographic analysis confirmed the structure of 1 and established the structure and absolute configuration of 5, while the absolute configurations for compounds 1, 4, and 6 were deduced by comparison of the CD data with those of S. Compounds 1, 2, 5, and 6 showed cytotoxic activities against several tumor cell lines. |
| 学科领域 | Plant Sciences ; Pharmacology & Pharmacy |
| DOI | 10.1021/np500382k |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000340861800021 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/24080 |
| 专题 | 实验海洋生物学重点实验室 |
| 通讯作者 | Huang, CG (reprint author), Second Mil Med Univ, Dept Biochem & Mol Biol, Xiangyin Rd 800, Shanghai 200433, Peoples R China. |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Second Mil Med Univ, Dept Biochem & Mol Biol, Shanghai 200433, Peoples R China |
| 第一作者单位 | 实验海洋生物学重点实验室 |
| 推荐引用方式 GB/T 7714 | Meng, Ling-Hong,Li, Xiao-Ming,Lv, Cui-Ting,et al. Brocazines A-F, Cytotoxic Bisthiodiketopiperazine Derivatives from Penicillium brocae MA-231, an Endophytic Fungus Derived from the Marine Mangrove Plant Avicennia marina[J]. JOURNAL OF NATURAL PRODUCTS,2014,77(8):1921-1927. |
| APA | Meng, Ling-Hong,Li, Xiao-Ming,Lv, Cui-Ting,Huang, Cai-Guo,Wang, Bin-Gui,&Huang, CG .(2014).Brocazines A-F, Cytotoxic Bisthiodiketopiperazine Derivatives from Penicillium brocae MA-231, an Endophytic Fungus Derived from the Marine Mangrove Plant Avicennia marina.JOURNAL OF NATURAL PRODUCTS,77(8),1921-1927. |
| MLA | Meng, Ling-Hong,et al."Brocazines A-F, Cytotoxic Bisthiodiketopiperazine Derivatives from Penicillium brocae MA-231, an Endophytic Fungus Derived from the Marine Mangrove Plant Avicennia marina".JOURNAL OF NATURAL PRODUCTS 77.8(2014):1921-1927. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Brocazines A-F, Cyto（1524KB） | 限制开放 | ODC PDDL | 浏览 | |||
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