A study of neuroprotective and antioxidant activities of heteropolysaccharides from six Sargassum species

doi:10.1016/j.ijbiomac.2014.03.031

IOCAS-IR > 实验海洋生物学重点实验室

	A study of neuroprotective and antioxidant activities of heteropolysaccharides from six Sargassum species
	Jin, Weihua 1,2; Zhang, Wenjing1,2 ; Wang, Jing1,3 ; Yao, Jianting 1; Xie, Enyi 4; Liu, Dongchao 4; Duan, Delin 1; Zhang, Quanbin 1; Zhang, QB (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
	2014-06-01
发表期刊	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷号	67 页码:336-342
文章类型	Article
摘要	Heteropolysaccharides were extracted from Sargassum integerrimum (S.I), Sargassum maclurei (S.M), Sargassum naozhouense (S.N), Spiraea thunbergii (S.T), Sargassum hemiphyllum (S.H) and Sargassum fusiforme (S.F), and their neuroprotective effects and antioxidant activities were investigated. It showed that S.I, S.N, S.T and S.F exhibited neuroprotective activities, whereas S.H and S.M did not. For this reason, they were separated by anion-exchange chromatography. It was apparent that the fraction 2 represented the principal difference between the active and non-active compounds. However, it did not correlate with neuroprotective effect. In addition, the results on antioxidant activities showed that the hydroxyl-radical scavenging effect contribute to the neuroprotective effect of S.T and S.N, and the DPPH-radical scavenging effect and reducing power contribute to S.T, S.F and S.I. However, the superoxide-radical scavenging effect did not correlate with neuroprotective activity. The conclusion was that the neuroprotective activity of the family of compounds investigated depended on a variety of factors. (C) 2014 Elsevier B.V. All rights reserved.
关键词	Neuroprotective Activity Antioxidant Activity Sargassum
学科领域	Biochemistry & Molecular Biology
DOI	10.1016/j.ijbiomac.2014.03.031
收录类别	SCI
语种	英语
WOS记录号	WOS:000336881200046
引用统计	被引频次：34[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/24063
专题	实验海洋生物学重点实验室海洋生物技术研发中心
通讯作者	Zhang, QB (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
作者单位	1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Nantong Branch, Inst Oceanol, Nantong 226006, Jiangsu, Peoples R China 4.Guangdong Ocean Univ, Coll Fisheries, Zhanjiang 524025, Peoples R China
第一作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Jin, Weihua,Zhang, Wenjing,Wang, Jing,et al. A study of neuroprotective and antioxidant activities of heteropolysaccharides from six Sargassum species[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2014,67:336-342.
APA	Jin, Weihua.,Zhang, Wenjing.,Wang, Jing.,Yao, Jianting.,Xie, Enyi.,...&Zhang, QB .(2014).A study of neuroprotective and antioxidant activities of heteropolysaccharides from six Sargassum species.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,67,336-342.
MLA	Jin, Weihua,et al."A study of neuroprotective and antioxidant activities of heteropolysaccharides from six Sargassum species".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 67(2014):336-342.

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