Multifunctional semiconducting polymer dots for imaging, detection, and photo-killing of bacteria

doi:10.1039/c4tb00288a

	Multifunctional semiconducting polymer dots for imaging, detection, and photo-killing of bacteria
	Wan, Yi 1; Zheng, Laibao2 ; Sun, Yan 1; Zhang, Dun 1; Zhang, D (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Marine Environm Corros & Biofouling, 7 Nanhai Rd, Qingdao 266071, Peoples R China.
	2014-08-14
发表期刊	JOURNAL OF MATERIALS CHEMISTRY B
卷号	2 期号:30 页码:4818-4825
文章类型	Article
摘要	Bacterial infections remain a key challenge in medicine and environment safety. Motivated by current clinical requirements, numerous diagnostic and therapeutic nanomaterials have emerged. Here, a family of agents, termed as antibiotic-based multifunctional semiconducting polymer dots (Pdots), which can detect bacteria with high sensitivity and selectively kill gram-positive bacteria or gram-negative bacteria, are reported. The multifunctional Pdots that exhibit good flexibility and stability at room temperature are usually small, and they can easily be modified to biomolecules. The highlight of this work is about how the developed bioconjugated Pdot system simultaneously possesses the abilities of detection, imaging, and pathogen photo-killing. This study not only demonstrates a facile approach to fabricate a bioconjugated probe for bacteria detection, but also provides a powerful and reliable platform for the photo-killing of pathogens, thus rendering potential broad antibacterial applications, bacteria diagnosis, and live-image assays.
学科领域	Materials Science
DOI	10.1039/c4tb00288a
收录类别	SCI
语种	英语
WOS记录号	WOS:000339469000006
引用统计	被引频次：32[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/23884
专题	海洋环境腐蚀与生物污损重点实验室
通讯作者	Zhang, D (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Marine Environm Corros & Biofouling, 7 Nanhai Rd, Qingdao 266071, Peoples R China.
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Environm Corros & Biofouling, Qingdao 266071, Peoples R China 2.Ocean Univ China Qingdao, Minist Educ, Key Lab Marine Chem Theory & Technol, Qingdao, Peoples R China
第一作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Wan, Yi,Zheng, Laibao,Sun, Yan,et al. Multifunctional semiconducting polymer dots for imaging, detection, and photo-killing of bacteria[J]. JOURNAL OF MATERIALS CHEMISTRY B,2014,2(30):4818-4825.
APA	Wan, Yi,Zheng, Laibao,Sun, Yan,Zhang, Dun,&Zhang, D .(2014).Multifunctional semiconducting polymer dots for imaging, detection, and photo-killing of bacteria.JOURNAL OF MATERIALS CHEMISTRY B,2(30),4818-4825.
MLA	Wan, Yi,et al."Multifunctional semiconducting polymer dots for imaging, detection, and photo-killing of bacteria".JOURNAL OF MATERIALS CHEMISTRY B 2.30(2014):4818-4825.

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