| Cold-active antibacterial and antifungal activities and antibiotic resistance of bacteria isolated from an alpine hydrocarbon-contaminated industrial site | |
| Hemala, Lydia1; Zhang, Dechao1,2; Margesin, Rosa1; Margesin, R (reprint author), Univ Innsbruck, Inst Microbiol, Technikerstr 25, A-6020 Innsbruck, Austria. | |
| 2014-07-01 | |
| 发表期刊 | RESEARCH IN MICROBIOLOGY
 |
| 卷号 | 165期号:6页码:447-456 |
| 文章类型 | Article |
| 摘要 | Selection pressure in hydrocarbon-contaminated soils may lead not only to increased microbial resistance to antibiotics, but also to increased capacity of the soil indigenous population to produce antimicrobial compounds. Therefore, we studied the antibiotic resistance pattern and antibacterial and/or antifungal activities of 47 bacterial strains isolated from an industrial alpine site heavily polluted with petroleum hydrocarbons. Resistance to penicillin was more widespread (49%) than resistance to chloramphenicol or rifampicin (28%) or streptomycin (26%). Only 9% of the strains were resistant to tetracycline. The ability to produce cold-active (10 degrees C) antimicrobial compounds was tested by using human pathogenic bacteria (Escherichia coli, Shigella flexneri, Salmonella enterica, Pseudomonas aeruginosa, Staphylococcus aureus) and yeasts (Candida albicans, Cryptococcus neoformans) as indicator microorganisms. About two-thirds of the 47 tested strains produced compounds that inhibited growth of at least one indicator microorganism. Six strains inhibited growth of both bacteria and yeast indicators; 12 and 16 strains showed either antibacterial or antifungal activity, respectively. The most versatile bacteria with regard to multiple antibiotic resistance and antimicrobial activity belonged to Actinobacteria or Gammaproteobacteria. The antimicrobial compounds produced by three Pseudomonas spp. and two Serratia spp. strains were characterized in more detail by TLC and HPLC. Depending on the sensitivity of growth inhibition to enzymes, the compounds produced by the three pseudomonads contained a proteinaceous component. (C) 2014 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved. |
| 关键词 | Antibiotics Antibacterial Antifungal Cold-active Hydrocarbons |
| 学科领域 | Microbiology |
| DOI | 10.1016/j.resmic.2014.05.035 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000347626000006 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/23768 |
| 专题 | 海洋生物分类与系统演化实验室 |
| 通讯作者 | Margesin, R (reprint author), Univ Innsbruck, Inst Microbiol, Technikerstr 25, A-6020 Innsbruck, Austria. |
| 作者单位 | 1.Univ Innsbruck, Inst Microbiol, A-6020 Innsbruck, Austria 2.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hemala, Lydia,Zhang, Dechao,Margesin, Rosa,et al. Cold-active antibacterial and antifungal activities and antibiotic resistance of bacteria isolated from an alpine hydrocarbon-contaminated industrial site[J]. RESEARCH IN MICROBIOLOGY,2014,165(6):447-456. |
| APA | Hemala, Lydia,Zhang, Dechao,Margesin, Rosa,&Margesin, R .(2014).Cold-active antibacterial and antifungal activities and antibiotic resistance of bacteria isolated from an alpine hydrocarbon-contaminated industrial site.RESEARCH IN MICROBIOLOGY,165(6),447-456. |
| MLA | Hemala, Lydia,et al."Cold-active antibacterial and antifungal activities and antibiotic resistance of bacteria isolated from an alpine hydrocarbon-contaminated industrial site".RESEARCH IN MICROBIOLOGY 165.6(2014):447-456. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Cold-active antibact（252KB） | 限制开放 | ODC PDDL | 浏览 | |||
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论