Aestivation in Nature: Physiological Strategies and Evolutionary Adaptations in Hypometabolic States

doi:10.3390/ijms241814093

	Aestivation in Nature: Physiological Strategies and Evolutionary Adaptations in Hypometabolic States
	Jiang, Chunxi 1,2,3; Storey, Kenneth B.4; Yang, Hongsheng1,2,3 ; Sun, Lina 1,2,3
	2023-09-01
发表期刊	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN	1661-6596
卷号	24 期号:18 页码:25
通讯作者	Sun, Lina(sunlina@qdio.ac.cn)
摘要	Aestivation is considered to be one of the "purest" hypometabolic states in nature, as it involves aerobic dormancy that can be induced and sustained without complex factors. Animals that undergo aestivation to protect themselves from environmental stressors such as high temperatures, droughts, and food shortages. However, this shift in body metabolism presents new challenges for survival, including oxidative stress upon awakening from aestivation, accumulation of toxic metabolites, changes in energy sources, adjustments to immune status, muscle atrophy due to prolonged immobility, and degeneration of internal organs due to prolonged food deprivation. In this review, we summarize the physiological and metabolic strategies, key regulatory factors, and networks utilized by aestivating animals to address the aforementioned components of aestivation. Furthermore, we present a comprehensive overview of the advancements made in aestivation research across major species, including amphibians, fish, reptiles, annelids, mollusks, and echinoderms, categorized according to their respective evolutionary positions. This approach offers a distinct perspective for comparative analysis, facilitating an understanding of the shared traits and unique features of aestivation across different groups of organisms.
关键词	aestivation hypometabolic states physiological strategies regulatory network
DOI	10.3390/ijms241814093
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[42076093] ; National Natural Science Foundation of China[42276143] ; Taishan Scholars Program
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
WOS类目	Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS记录号	WOS:001145166800001
出版者	MDPI
WOS关键词	CUCUMBER APOSTICHOPUS-JAPONICUS ; AFRICAN CLAWED FROG ; STRIPED BURROWING FROG ; LUNGFISH PROTOPTERUS-ANNECTENS ; HORMOGASTER-ELISAE OLIGOCHAETA ; DIFFERENTIAL GENE-EXPRESSION ; INCREASED UREA SYNTHESIS ; AMINO-ACID-METABOLISM ; SNAIL THEBA-PISANA ; SEA-CUCUMBER
引用统计
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/184396
专题	海洋生态与环境科学重点实验室
通讯作者	Sun, Lina
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci & Expt Mari, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci & Marine Biol & Bio, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Carleton Univ, Dept Biol, Ottawa, ON K1S 5B6, Canada
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Jiang, Chunxi,Storey, Kenneth B.,Yang, Hongsheng,et al. Aestivation in Nature: Physiological Strategies and Evolutionary Adaptations in Hypometabolic States[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2023,24(18):25.
APA	Jiang, Chunxi,Storey, Kenneth B.,Yang, Hongsheng,&Sun, Lina.(2023).Aestivation in Nature: Physiological Strategies and Evolutionary Adaptations in Hypometabolic States.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,24(18),25.
MLA	Jiang, Chunxi,et al."Aestivation in Nature: Physiological Strategies and Evolutionary Adaptations in Hypometabolic States".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 24.18(2023):25.