Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel <i>Gigantidas platifrons</i> under a deep-sea mining activity scenario

doi:10.1007/s00343-023-3048-y

	*Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel Gigantidas platifrons* under a deep-sea mining activity scenario**
	Zhou, Li 1; Li, Mengna 1,4,5; Zhong, Zhaoshan1 ; Wang, Minxiao 1; Chen, Hao1 ; Lian, Chao 1,2; Wang, Hao 1; Zhang, Huan 1; Cao, Lei1 ; Li, Chaolun1,3,4,5
	2024-01-11
发表期刊	JOURNAL OF OCEANOLOGY AND LIMNOLOGY
ISSN	2096-5508
页码	11
通讯作者	Li, Chaolun(lcl@qdio.ac.cn)
摘要	Deep-sea mining activities can potentially release metals, which pose a toxicological threat to deep-sea ecosystems. Nevertheless, due to the remoteness and inaccessibility of the deep-sea biosphere, there is insufficient knowledge about the impact of metal exposure on its inhabitants. In this study, deep-sea mussel Gigantidas platifrons, a commonly used deep-sea toxicology model organism, was exposed to manganese (100, 1 000 mu g/L) or iron (500, 5 000 mu g/L) for 7 d, respectively. Manganese and iron were chosen for their high levels of occurrence within deep-sea deposits. Metal accumulation and a battery of biochemical biomarkers that related to antioxidative stress in superoxide dismutase (SOD), catalase (CAT), malondialdehyde (MDA); immune function in alkaline phosphatase (AKP), acid phosphatase (ACP); and energy metabolism in pyruvate kinase (PK) and hexokinase (HK) were assessed in mussel gills. Results showed that deep-sea mussel G. platifrons exhibited high capacity to accumulate Mn/Fe. In addition, most tested biochemical parameters were altered by metal exposure, demonstrating that metals could induce oxidative stress, suppress the immune system, and affect energy metabolism of deep-sea mussels. The integrated biomarker response (IBR) approach indicated that the exposure to Mn/Fe had a negative impact on deep-sea mussels, and Mn demonstrated a more harmful impact on deep-sea mussels than Fe. Additionally, SOD and CAT biomarkers had the greatest impact on IBR values in Mn treatments, while ACP and HK were most influential for the low- and high-dose Fe groups, respectively. This study represents the first application of the IBR approach to evaluate the toxicity of metals on deep-sea fauna and serves as a crucial framework for risk assessment of deep-sea mining-associated metal exposure.
关键词	mussel metal deep-sea mining biomarker environmental monitoring
DOI	10.1007/s00343-023-3048-y
收录类别	SCI
语种	英语
资助项目	Marine S&T Fund of Shandong Province for Qingdao Marine Science and Technology Center[2022QNLM030004-1] ; National Natural Science Foundation of China[42276153] ; National Natural Science Foundation of China[42030407] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDB42020401] ; Key Research Program of Frontier Sciences, CAS[ZDBS-LY-DQC032] ; National Key R&D program of China[2022YFC2804003]
WOS研究方向	Marine & Freshwater Biology ; Oceanography
WOS类目	Limnology ; Oceanography
WOS记录号	WOS:001141710300012
出版者	SCIENCE PRESS
WOS关键词	ALKALINE-PHOSPHATASE ACTIVITY ; OXIDATIVE STRESS ; HEAVY-METALS ; SCROBICULARIA-PLANA ; LIPID-PEROXIDATION ; USEFUL TOOL ; COPPER ; CADMIUM ; ENZYMES ; HOMEOSTASIS
引用统计
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/184312
专题	深海极端环境与生命过程研究中心海洋生态与环境科学重点实验室
通讯作者	Li, Chaolun
作者单位	1.Chinese Acad Sci, Ctr Deep Sea Res, Inst Oceanol, Qingdao 266071, Peoples R China 2.Laoshan Lab, Qingdao 266237, Peoples R China 3.Chinese Acad Sci, South China Sea Inst Oceanol, Guangzhou 510301, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所; 海洋生态与环境科学重点实验室
推荐引用方式 GB/T 7714	Zhou, Li,Li, Mengna,Zhong, Zhaoshan,et al. Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel Gigantidas platifrons under a deep-sea mining activity scenario[J]. JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2024:11.
APA	Zhou, Li.,Li, Mengna.,Zhong, Zhaoshan.,Wang, Minxiao.,Chen, Hao.,...&Li, Chaolun.(2024).Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel Gigantidas platifrons under a deep-sea mining activity scenario.JOURNAL OF OCEANOLOGY AND LIMNOLOGY,11.
MLA	Zhou, Li,et al."Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel Gigantidas platifrons under a deep-sea mining activity scenario".JOURNAL OF OCEANOLOGY AND LIMNOLOGY (2024):11.