A self-powered biosensor based on triboelectric nanogenerator for dual-specificity bacterial detection

doi:10.1002/inf2.12508

IOCAS-IR

	A self-powered biosensor based on triboelectric nanogenerator for dual-specificity bacterial detection
	Lu, Wei 1; Wang, Xiaoqiang 1; Wang, Congyu 2; Gong, Ke 3; Li, Jiawei 2; Li, Xue 4; Wang, Peng2,5
	2023-12-15
发表期刊	INFOMAT
页码	14
通讯作者	Wang, Xiaoqiang(wangxq001@upc.edu.cn) ; Wang, Peng(wangpeng@qdio.ac.cn)
摘要	Pathogenic and corrosive bacteria pose a significant risk to human health or economic well-being. The specific, sensitive, and on-site detection of these bacteria is thus of paramount significance but remains challenging. Taking inspiration from immunoassays with primary and secondary antibodies, we describe here a rational design of microbial sensor (MS) under a dual-specificity recognition strategy using Pseudomonas aeruginosa (P. aeruginosa) as the detection model. In the MS, engineered aptamers are served as the primary recognition element, while polydopamine-N-acetyl-D-galactosamine (PDA-Gal NAc) nanoparticles are employed as the secondary recognition element, which will also generate and amplify changes in the output voltage signal. To achieve self-powering capability, the MS is constructed based on a triboelectric nanogenerator (TENG) with the specific aptamers immobilized on the TENG electrode surface. The as-prepared MS-TENG system exhibits good stability in output performance under external forces, and high specificity toward P. aeruginosa, with no cross-reactivity observed. A linear relationship (R-2 = 0.995) between the output voltage and P. aeruginosa concentration is established, with a limit of detection estimated at around 8.7 x 10(3) CFU mL(-1). The utilization of PDA-Gal NAc nanoparticles is found to play an important role in enhancing the specific and reliability of detection, and the underlying mechanisms are further clarified by computational simulations. In addition, the MS-TENG integrates a wireless communication module, enabling real-time monitoring of bacterial concentration on mobile devices. This work introduces a pioneering approach to designing self-powered smart microbial sensors with high specificity, using a double recognition strategy applicable to various bacteria beyond P. aeruginosa. image
关键词	bacterial detection high specificity microbial sensor triboelectric nanogenerator wireless transmission
DOI	10.1002/inf2.12508
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China ; Guangxi Natural Science Foundation[2023GXNSFDA026059] ; [42276216]
WOS研究方向	Materials Science
WOS类目	Materials Science, Multidisciplinary
WOS记录号	WOS:001125463500001
出版者	WILEY
WOS关键词	PSEUDOMONAS-AERUGINOSA ; SENSITIVE DETECTION
引用统计
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/184174
专题	中国科学院海洋研究所
通讯作者	Wang, Xiaoqiang; Wang, Peng
作者单位	1.China Univ Petr East China, Coll Chem & Chem Engn, State Key Lab Heavy Oil Proc, Qingdao 266580, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 3.China Univ Petr East China, Sch Mat Sci & Engn, Qingdao, Peoples R China 4.Shandong Univ, State Key Lab Microbial Technol, Qingdao, Peoples R China 5.Guangxi Acad Sci, Nanning, Peoples R China
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Lu, Wei,Wang, Xiaoqiang,Wang, Congyu,et al. A self-powered biosensor based on triboelectric nanogenerator for dual-specificity bacterial detection[J]. INFOMAT,2023:14.
APA	Lu, Wei.,Wang, Xiaoqiang.,Wang, Congyu.,Gong, Ke.,Li, Jiawei.,...&Wang, Peng.(2023).A self-powered biosensor based on triboelectric nanogenerator for dual-specificity bacterial detection.INFOMAT,14.
MLA	Lu, Wei,et al."A self-powered biosensor based on triboelectric nanogenerator for dual-specificity bacterial detection".INFOMAT (2023):14.

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A self‐powered biose（8995KB）	期刊论文	出版稿	限制开放	CC BY-NC-SA	浏览