Identification, classification and expression analysis of the Ras superfamily genes in the Pacific white shrimp, Litopenaeus vannamei

doi:10.3389/fmars.2023.1063857

IOCAS-IR > 实验海洋生物学重点实验室

	Identification, classification and expression analysis of the Ras superfamily genes in the Pacific white shrimp, Litopenaeus vannamei
	Si, Shuqing 1,2,3; Zhang, Xiaojun 1,2,3,4,5; Yuan, Jianbo 2,3,4,5; Zhang, Xiaoxi2,3,4,5 ; Yu, Yang2,3,4,5 ; Yang, Song 1; Li, Fuhua 2,3,4,5
	2023-01-23
发表期刊	FRONTIERS IN MARINE SCIENCE
卷号	10 页码:17
通讯作者	Zhang, Xiaojun(xjzhang@qdio.ac.cn) ; Yang, Song(yangsong1209@163.com)
摘要	The Ras superfamily of small guanosine triphosphatases (GTPases) are a large group of small GTP-binding proteins, which play crucial roles in basic cellular processes in all eukaryotes. In this study, by analyzing the gene structure, temporal and spatial expression patterns, a total of 108 Ras superfamily genes were identified in the genome of the Pacific white shrimp Litopenaeus vannamei. We found these genes included not only the classical Ras GTPase superfamily members, but also some unconventional and novel Ras GTPase proteins, which have unknown functions and unique expression patterns. All Ras superfamily genes of L. vannamei were highly conserved within the core G domain and closely related in phylogeny, but they might have two different evolutionary origins. In addition, different Ras GTPase genes exhibited distinct expression patterns in different tissues, development/molting stages and WSSV infection samples of L. vannamei, suggesting that they may have a high functional specialization, and play important roles in regulating the biological processes of cell differentiation, growth and development, immune response, etc. This study provides important clues for the structure, classification, evolution and function of Ras superfamily in shrimp.
关键词	Ras superfamily GTPase proteins Litopenaeus vannamei gene structure and function gene expression immunity growth
DOI	10.3389/fmars.2023.1063857
收录类别	SCI
语种	英语
资助项目	Strategic Priority Research Program of the Chinese Academy of Sciences[XDA24030105] ; National Key R&D Program of China[2018YFD0900103] ; National Key R&D Program of China[2022YFF1000304] ; National Natural Sciences Foundation of China[31972782] ; National Natural Sciences Foundation of China[32273102]
WOS研究方向	Environmental Sciences & Ecology ; Marine & Freshwater Biology
WOS类目	Environmental Sciences ; Marine & Freshwater Biology
WOS记录号	WOS:000924629800001
出版者	FRONTIERS MEDIA SA
WOS关键词	SMALL GTPASES ; NEURONAL DIFFERENTIATION ; ACTIVATING PROTEINS ; CRYSTAL-STRUCTURE ; RHO-GTPASES ; FAMILY ; TRANSPORT ; PHAGOCYTOSIS ; COMPLEX ; MEMBER
引用统计
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/183416
专题	实验海洋生物学重点实验室
通讯作者	Zhang, Xiaojun; Yang, Song
作者单位	1.Qingdao Agr Univ, Sch Life & Sci, Qingdao, Peoples R China 2.Inst Oceanol, Chinese Acad Sci, Qingdao, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Shandong Prov Key Lab Expt Marine Biol, Qingdao, Peoples R China 4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China 5.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Si, Shuqing,Zhang, Xiaojun,Yuan, Jianbo,et al. Identification, classification and expression analysis of the Ras superfamily genes in the Pacific white shrimp, Litopenaeus vannamei[J]. FRONTIERS IN MARINE SCIENCE,2023,10:17.
APA	Si, Shuqing.,Zhang, Xiaojun.,Yuan, Jianbo.,Zhang, Xiaoxi.,Yu, Yang.,...&Li, Fuhua.(2023).Identification, classification and expression analysis of the Ras superfamily genes in the Pacific white shrimp, Litopenaeus vannamei.FRONTIERS IN MARINE SCIENCE,10,17.
MLA	Si, Shuqing,et al."Identification, classification and expression analysis of the Ras superfamily genes in the Pacific white shrimp, Litopenaeus vannamei".FRONTIERS IN MARINE SCIENCE 10(2023):17.