A dual-emission ratiometric fluorescent sensor based on copper nanoclusters encapsulated in zeolitic imidazolate framework-90 for rapid detection and imaging of adenosine triphosphate

doi:10.1039/d2ay01932a

	A dual-emission ratiometric fluorescent sensor based on copper nanoclusters encapsulated in zeolitic imidazolate framework-90 for rapid detection and imaging of adenosine triphosphate
	Xin, Yue 1,2,3; Zhang, Dun 1,2,3; Zeng, Yan1,3 ; Wang, Yingwen 1,2,3; Qi, Peng1,2,3
	2023-02-09
发表期刊	ANALYTICAL METHODS
ISSN	1759-9660
卷号	15 期号:6 页码:788-796
通讯作者	Zhang, Dun(zhangdun@qdio.ac.cn) ; Qi, Peng(qipeng@qdio.ac.cn)
摘要	Adenosine triphosphate (ATP) is the primary energy carrier for intracellular metabolic processes. Accurate and rapid detection of ATP has important implications for clinical diagnosis. In this work, we reported a dual-emission ratiometric fluorescent probe Cu NCs-Al@ZIF-90 formed by encapsulating copper nanoclusters (Cu NCs) into zeolitic imidazolate framework-90 (ZIF-90) using a simple one-pot method. Cu NCs exhibited a remarkable fluorescence enhancement in the presence of aluminum ions due to the aggregation-induced emission (AIE) properties. When ATP existed, the Zn2+ nodes in the MOF material acted as selective sites for ATP recognition, resulting in the cleavage of Cu NCs-Al@ZIF-90. As a consequence, two reverse fluorescence changes were observed from released Cu NCs at 620 nm and imidazole-2-carboxaldehyde (2-ICA) at 450 nm, respectively. With the dual-emission ratiometric strategy, efficient and rapid determination of ATP was realized, giving a detection limit down to 0.034 mM in the concentration range of 0.2 mM to 0.625 mM. The convenient synthesis process and the rapid ATP-responsive ability made the proposed Cu NCs-Al@ZIF-90 probe highly promising in clinical and environmental analysis.
DOI	10.1039/d2ay01932a
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[41876101] ; National Natural Science Foundation of China[41906037] ; Nantong Scientific Plan Foundation[JC2021054] ; Nantong Scientific Plan Foundation[JC2020090] ; Open fund of Wenzhou Key Laboratory of Sanitary Microbiology[ZD202003KF01] ; Shandong Provincial Marine Science and Technology Projects
WOS研究方向	Chemistry ; Food Science & Technology ; Spectroscopy
WOS类目	Chemistry, Analytical ; Food Science & Technology ; Spectroscopy
WOS记录号	WOS:000917721300001
出版者	ROYAL SOC CHEMISTRY
WOS关键词	ATP ; PROBE ; CELLS ; CHEMOSENSORS ; MITOCHONDRIA ; APTAMER ; RANGE
引用统计	被引频次：7[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/183395
专题	海洋环境腐蚀与生物污损重点实验室
通讯作者	Zhang, Dun; Qi, Peng
作者单位	1.Inst Oceanol, Chinese Acad Sci, Key Lab Marine Environm Corros & Biofouling, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 3.Pilot Natl Lab Marine Sci & Technol, Open Studio Marine Corros & Protect, Qingdao 266237, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Xin, Yue,Zhang, Dun,Zeng, Yan,et al. A dual-emission ratiometric fluorescent sensor based on copper nanoclusters encapsulated in zeolitic imidazolate framework-90 for rapid detection and imaging of adenosine triphosphate[J]. ANALYTICAL METHODS,2023,15(6):788-796.
APA	Xin, Yue,Zhang, Dun,Zeng, Yan,Wang, Yingwen,&Qi, Peng.(2023).A dual-emission ratiometric fluorescent sensor based on copper nanoclusters encapsulated in zeolitic imidazolate framework-90 for rapid detection and imaging of adenosine triphosphate.ANALYTICAL METHODS,15(6),788-796.
MLA	Xin, Yue,et al."A dual-emission ratiometric fluorescent sensor based on copper nanoclusters encapsulated in zeolitic imidazolate framework-90 for rapid detection and imaging of adenosine triphosphate".ANALYTICAL METHODS 15.6(2023):788-796.