Structural properties, anti-fatigue and immunological effect of low molecular weight peptide from Monkfish

doi:10.1016/j.jff.2023.105546

IOCAS-IR > 实验海洋生物学重点实验室

	Structural properties, anti-fatigue and immunological effect of low molecular weight peptide from Monkfish
	Wang, Xueqin ; Yu, Huahua; Xing, Ronge; Liu, Song ; Chen, Xiaolin ; Li, Pengcheng1
	2023-06-01
发表期刊	JOURNAL OF FUNCTIONAL FOODS
ISSN	1756-4646
卷号	105 页码:12
通讯作者	Li, Pengcheng(pcli@qdio.ac.cn)
摘要	Monkfish (Lophius litulon) is a nutritious marine product that has attracted increasing attention. In this study, we demonstrated that the monkfish protein hydrolysate (MPH) administration could significantly prolonged the exhaustive swimming time of mice, and increased the hepatic glycogen (HG) level, superoxide dismutase (SOD), catalase (CAT), and glutathione peroxides (GSH-PX) activities; in addition, markedly decreased the blood urea nitrogen (BUN), blood lactic acid (BLA), malonaldehyde (MDA) levels and lactate dehydrogenase (LDH) activity. Furthermore, the MPH administration also enhanced the proliferation of spleen lymphocytes and the activity of natural killer (NK) cells in mice. Besides, 43 peptides from MPH that rich in Phe, His, Ile, Leu and Thr were identified. Finally, 1245 of differentially expressed genes (DEGs) in NC vs MPH-H groups were obtained by transcriptome analysis, and GO classification and enrichment of KEGG pathway were studied. In conclusion, MPH treatment had the anti-fatigue and immunological effects in mice.
关键词	Monkfish Purification exercise-induced fatigue Immunological effect Transcriptome analysis
DOI	10.1016/j.jff.2023.105546
收录类别	SCI
语种	英语
资助项目	Key Projects for Major Projects on the Transformation of Old and Novel Kinetic Energy of Shandong Province[2020-1220] ; STS Project of the Chinese Academy of Sciences[2021T3038]
WOS研究方向	Food Science & Technology ; Nutrition & Dietetics
WOS类目	Food Science & Technology ; Nutrition & Dietetics
WOS记录号	WOS:000989717000001
出版者	ELSEVIER
WOS关键词	ANTIOXIDANT PEPTIDES ; PROTEIN HYDROLYSATE ; PURIFICATION ; IDENTIFICATION ; EXTRACTS ; ACID ; MICE
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/183136
专题	实验海洋生物学重点实验室
通讯作者	Li, Pengcheng
作者单位	1.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, CAS & Shandong Prov Key Lab Expt Marine Biol, 7 Nanhai Rd, Qingdao 266071, Peoples R China 2.Pilot Natl Lab Marine Sci & Technol Qingdao, Lab Marine Drugs & Bioprod, 1 Wenhai Rd, Qingdao 266237, Peoples R China
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Wang, Xueqin,Yu, Huahua,Xing, Ronge,et al. Structural properties, anti-fatigue and immunological effect of low molecular weight peptide from Monkfish[J]. JOURNAL OF FUNCTIONAL FOODS,2023,105:12.
APA	Wang, Xueqin,Yu, Huahua,Xing, Ronge,Liu, Song,Chen, Xiaolin,&Li, Pengcheng.(2023).Structural properties, anti-fatigue and immunological effect of low molecular weight peptide from Monkfish.JOURNAL OF FUNCTIONAL FOODS,105,12.
MLA	Wang, Xueqin,et al."Structural properties, anti-fatigue and immunological effect of low molecular weight peptide from Monkfish".JOURNAL OF FUNCTIONAL FOODS 105(2023):12.