A self-powered biosensing system based on triboelectric nanogenerator for rapid bacterial DNA detection

doi:10.1016/j.snb.2023.133917

	A self-powered biosensing system based on triboelectric nanogenerator for rapid bacterial DNA detection
	Qu, Xiaolin 1,2,3; Qi, Peng2,3 ; Wang, Peng2,3 ; Li, Jiawei 2,3; Wang, Congyu 2,3; Zhang, Dun 2,3; Wan, Yi 4; Ai, Shiyun 5; Wang, Xiaoqiang 1
	2023-09-01
发表期刊	SENSORS AND ACTUATORS B-CHEMICAL
卷号	390 页码:12
通讯作者	Wang, Peng(wangpeng@qdio.ac.cn) ; Wang, Xiaoqiang(wangxq001@upc.edu.cn)
摘要	A self-powered biosensing system based on triboelectric nanogenerator (TENG) for bacterial DNA detection is invented and a vertical contact-separation TENG was designed to provide a steady power supply to a detection bioreactor. A carboxyl-functionalized capture probe was modified on etched indium tin oxide (ITO) glass, with which target bacterial DNA could be recognized. Meanwhile, multi-walled carbon-nanotubes (CNT)-modified signal probe was designed to amplify the detection signal due to its excellent electrical conductivity. The selfpowered biosensing system could measure the variation in output voltage and be highly sensible with a low detection limit at 0.084 pM of target DNA. In addition, a mathematical model based on the Freundlich isotherm was built to simulate the DNA detection process, and it was feasible to simulate the calibration equation and detection range. A portable self-powered biosensing device was made by integrating miniaturized TENG and bioreactor in a 3D-printed mold, with which the presence of bacterial DNA could be instantly indicated by LED (light-emitting diode). This study provided a useful platform for quick bacterial DNA detection and paved the way for further development of pocket diagnosis with TENG-based biosensing systems.
关键词	Triboelectric nanogenerator Self-powering DNA biosensor Bacterial DNA Mathematical model
DOI	10.1016/j.snb.2023.133917
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[XDA23050104] ; Strategic Priority Research Program of Chinese Academy of Sciences ; Shandong Provincial Marine Science and Technology Projects of 2018 ; [41922040]
WOS研究方向	Chemistry ; Electrochemistry ; Instruments & Instrumentation
WOS类目	Chemistry, Analytical ; Electrochemistry ; Instruments & Instrumentation
WOS记录号	WOS:001053182900001
出版者	ELSEVIER SCIENCE SA
WOS关键词	SULFATE-REDUCING BACTERIA ; REAL-TIME ; ULTRASENSITIVE DETECTION ; MICROFLUIDIC PLATFORM ; HEALTHY-SUBJECTS ; LABEL-FREE ; SENSOR ; ADSORPTION ; CHEMILUMINESCENCE ; NANOPARTICLES
引用统计	被引频次：7[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/182868
专题	海洋环境腐蚀与生物污损重点实验室
通讯作者	Wang, Peng; Wang, Xiaoqiang
作者单位	1.China Univ Petr East China, Coll Chem & Chem Engn, State Key Lab Heavy Oil Proc, Qingdao 266580, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Environm Corros & Biofouling, Qingdao 266071, Peoples R China 3.Pilot Natl Lab Marine Sci & Technol Qingdao, Open Studio Marine Corros & Protect, 168 Wenhai Middle Rd, Qingdao 266237, Peoples R China 4.Hainan Univ, State Key Lab Marine Resource Utilizat South Chin, Key Lab Trop Biol Resources, Marine Coll,Minist Educ,Sch Life & Pharmaceut Sci, 56 Renmin Rd, Haikou 570228, Hainan, Peoples R China 5.Shandong Agr Univ, Coll Chem & Mat Sci, Food Safety Anal & Test Engn Technol Res Ctr Shand, Tai An 271018, Shandong, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Qu, Xiaolin,Qi, Peng,Wang, Peng,et al. A self-powered biosensing system based on triboelectric nanogenerator for rapid bacterial DNA detection[J]. SENSORS AND ACTUATORS B-CHEMICAL,2023,390:12.
APA	Qu, Xiaolin.,Qi, Peng.,Wang, Peng.,Li, Jiawei.,Wang, Congyu.,...&Wang, Xiaoqiang.(2023).A self-powered biosensing system based on triboelectric nanogenerator for rapid bacterial DNA detection.SENSORS AND ACTUATORS B-CHEMICAL,390,12.
MLA	Qu, Xiaolin,et al."A self-powered biosensing system based on triboelectric nanogenerator for rapid bacterial DNA detection".SENSORS AND ACTUATORS B-CHEMICAL 390(2023):12.