miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon (Salmo salar) by Targeting Brain-Derived Neurotrophic Factor

doi:10.3390/fishes8070345

IOCAS-IR > 实验海洋生物学重点实验室

	miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon (Salmo salar) by Targeting Brain-Derived Neurotrophic Factor
	Guo, Teng 1,2; Wang, Yanfeng 3,4; Jiang, Ping 5; Li, Jun 2,3,6; Liu, Qinghua 3,4; Chi, Liang 1
	2023-07-01
发表期刊	FISHES
卷号	8 期号:7 页码:14
通讯作者	Liu, Qinghua(qinghualiu@qdio.ac.cn) ; Chi, Liang(lchi@qau.edu.cn)
摘要	This study was designed to explore the impact of the photoperiod on the gonadal development and somatic growth of Atlantic salmon raised in recirculating aquaculture systems (RASs), with specific focus on the role that microRNA (miR)-155 plays as a regulator in the Atlantic salmon's photoperiodic reproduction. These salmon were reared for 5 months under six different photoperiod regimens, including two with changing photoperiods (LL-SL = 24L:0D-8L:16D and SL-LL = 8L:16D-24L:0D) and four with constant photoperiods (24L:0D, 18L:6D, 12L:12D, and 8L:16D). The longer photoperiod groups (LL-SL and 24L:0D) were ultimately associated with higher gonadosomatic index (GSI) values and an increased proportion of mature fish relative to other exposure groups, indicating that the photoperiod positively impacted the Atlantic salmon's gonadal development in RAS environments. Hypothalamic miR-155 expression in these Atlantic salmon was also found to be influenced by the photoperiod, showing a markedly decreased expression in salmon exposed to a long photoperiod and upregulation following rearing under a short photoperiod. Functionally, miR-155 was found to suppress the expression of gonadal axis-related genes, including FSH and GnRH, through its ability to target the brain-derived neurotrophic factor (BDNF) and to thereby regulate photoperiod reproduction. Overall, these results suggested that the photoperiod could regulate gonad development in Atlantic salmon with miRNA-155 being involved in this process by targeting the BDNF.
关键词	photoperiod gonad development microRNA-155 recirculating aquaculture system Atlantic salmon
DOI	10.3390/fishes8070345
收录类别	SCI
语种	英语
资助项目	National Key Research and Development Program[2018YFD0901204] ; China Agriculture Research System[CARS-47-G21] ; STS Project[KFZD-SW-106] ; STS Project[ZSSD-019] ; STS Project[2017T3017] ; STS Project[KFJ-STS-QYZX-020] ; Qingdao National Laboratory for Marine Science and Technology[2018SDKJ0502-2] ; Qingdao National Laboratory for Marine Science and Technology[2015ASKJ02] ; National Natural Science Foundation of China[31402283] ; Agricultural Application Technology Innovation Project of Shandong Province[31672672] ; [SD2019YY011]
WOS研究方向	Fisheries ; Marine & Freshwater Biology
WOS类目	Fisheries ; Marine & Freshwater Biology
WOS记录号	WOS:001038654200001
出版者	MDPI
WOS关键词	CURRENT KNOWLEDGE ; GROWTH ; SEAWATER ; FISH ; MATURATION ; PHYSIOLOGY ; ENDOCRINE ; MELATONIN ; PUBERTY ; SYSTEMS
引用统计
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/182638
专题	实验海洋生物学重点实验室
通讯作者	Liu, Qinghua; Chi, Liang
作者单位	1.Qingdao Agr Univ, Coll Vet Med, Qingdao 266109, Peoples R China 2.Qingdao Agr Univ, Coll Life Sci, Qingdao 266109, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Peoples R China 5.Jinan Ctr Anim Dis Prevent & Control, Jinan 250109, Peoples R China 6.Southern Marine Sci & Engn Guangdong Lab, Guangzhou 511458, Peoples R China
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Guo, Teng,Wang, Yanfeng,Jiang, Ping,et al. miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon (Salmo salar) by Targeting Brain-Derived Neurotrophic Factor[J]. FISHES,2023,8(7):14.
APA	Guo, Teng,Wang, Yanfeng,Jiang, Ping,Li, Jun,Liu, Qinghua,&Chi, Liang.(2023).miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon (Salmo salar) by Targeting Brain-Derived Neurotrophic Factor.FISHES,8(7),14.
MLA	Guo, Teng,et al."miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon (Salmo salar) by Targeting Brain-Derived Neurotrophic Factor".FISHES 8.7(2023):14.