Differentiation and decreased genetic diversity in field contaminated oysters Crassostrea hongkongensis: Identification of selection signatures*

doi:10.1016/j.envpol.2023.122101

IOCAS-IR > 实验海洋生物学重点实验室

	Differentiation and decreased genetic diversity in field contaminated oysters Crassostrea hongkongensis: Identification of selection signatures*
	Meng, Jie1,2,3,4 ; Wang, Wen-Xiong 1,2,5
	2023-09-15
发表期刊	ENVIRONMENTAL POLLUTION
ISSN	0269-7491
卷号	333 页码:12
通讯作者	Wang, Wen-Xiong(wx.wang@cityu.edu.hk)
摘要	The extent to which chemical contamination affects the population structure and genetic diversity of natural populations remains elusive. Here, we used the whole-genome resequencing and transcriptome to diagnose the effects of long-term exposure to multiple elevated chemical pollutants on the population differentiation and genetic diversity in oysters Crassostrea hongkongensis in a typically polluted Pearl River Estuary (PRE) of Southern China. Population structure revealed an obvious differentiation between the PRE oysters and those collected from a nearby clean Beihai (BH) individuals, while no significant differentiation was observed among individuals collected from the three pollution sites within PRE due to the high gene flow. The decreased genetic diversity in the PRE oysters reflected the long-term effects of chemical pollutants. Selective sweeps between BH and PRE oysters revealed that chemical defensome genes, including glutathione S-transferase, zinc transporter, were responsible for their differentiation, sharing common metabolic process of other pollutants. Combined with the genome-wide association analysis, 25 regions containing 77 genes were identified to be responsible for the direct selection regions of metals. Linkage disequilibrium blocks and haplotypes within these regions provided the biomarkers of permanent effects. Our results provide important insights to the genetic mechanisms underlying the rapid evolution under chemical contamination in marine bivalves.
关键词	Oyster Population structure Genetic diversity Selective sweeps Metal GWAS
DOI	10.1016/j.envpol.2023.122101
收录类别	SCI
语种	英语
资助项目	Youth Innovation Promotion Association of the Chinese Academy of Science, China[2019210] ; National Natural Science Foundation of China, China[32102815]
WOS研究方向	Environmental Sciences & Ecology
WOS类目	Environmental Sciences
WOS记录号	WOS:001034456200001
出版者	ELSEVIER SCI LTD
WOS关键词	GENOME-WIDE ASSOCIATION ; METALS POLLUTION ; POPULATIONS ; ADAPTATION ; RESISTANCE ; RESPONSES ; HERITABILITY ; VARIABILITY ; TOLERANCE ; EVOLUTION
引用统计
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/182530
专题	实验海洋生物学重点实验室
通讯作者	Wang, Wen-Xiong
作者单位	1.City Univ Hong Kong, Sch Energy & Environm, Hong Kong, Peoples R China 2.City Univ Hong Kong, State Key Lab Marine Pollut, Hong Kong, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Peoples R China 4.Key Lab Breeding Biotechnol & Sustainable Aquacult, Wuhan, Peoples R China 5.City Univ Hong Kong, Res Ctr Oceans & Human Hlth, Shenzhen Res Inst, Shenzhen 518057, Peoples R China
第一作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Meng, Jie,Wang, Wen-Xiong. Differentiation and decreased genetic diversity in field contaminated oysters Crassostrea hongkongensis: Identification of selection signatures*[J]. ENVIRONMENTAL POLLUTION,2023,333:12.
APA	Meng, Jie,&Wang, Wen-Xiong.(2023).Differentiation and decreased genetic diversity in field contaminated oysters Crassostrea hongkongensis: Identification of selection signatures*.ENVIRONMENTAL POLLUTION,333,12.
MLA	Meng, Jie,et al."Differentiation and decreased genetic diversity in field contaminated oysters Crassostrea hongkongensis: Identification of selection signatures*".ENVIRONMENTAL POLLUTION 333(2023):12.