Correlation study of SNP of glycogen degradation metabolism related genes and glycogen content in Haliotis discus hannai

doi:10.1016/j.aquaculture.2023.740022

IOCAS-IR > 实验海洋生物学重点实验室

	Correlation study of SNP of glycogen degradation metabolism related genes and glycogen content in Haliotis discus hannai
	Tang, Xueying 1; Li, Sisi 1; Zhuo, Ling 1; Zhang, Qingya 1; Wu, Fucun 2; Lin, Siheng1
	2024-01-15
发表期刊	AQUACULTURE
ISSN	0044-8486
卷号	578 页码:7
通讯作者	Lin, Siheng(sihengdg@gmail.com)
摘要	Glycogen is an essential nutritional component of the Pacific abalone (Haliotis discus hannai), and its content is a crucial factor in selecting and breeding high-quality abalone. Glycogen catabolism is facilitated by two key enzymes: glycogen debranching enzyme (GDE) and glycogen phosphorylase (GP). This study aimed to explore the relationship between GDE and GP gene polymorphisms and glycogen content in abalone. To this end, four and two SNP loci located in the exonic regions of these two genes, respectively, were screened and identified in 264 abalone using direct sequencing. The results of genetic polymorphism and correlation analysis revealed a negative correlation between the expression of GDE and GP and glycogen content. Moreover, the study found that the GA haplotype of GDE gene SNP1/3 was significantly associated with high glycogen content, while the TT genotype of GP gene SNP2 was significantly associated with low glycogen content. These results provide molecular markers that could be utilized for selecting and breeding glycogen traits in abalone, indicating the potential influence of GDE and GP polymorphisms on glycogen content.
关键词	Haliotis discus hannai Glycogen content SNP Glycogen debranching enzyme Glycogen phosphorylase
DOI	10.1016/j.aquaculture.2023.740022
收录类别	SCI
语种	英语
资助项目	Natural Science Foundation of Fujian Province[2020 J05167] ; Key Cultivation Project of Minnan Normal University[4206/L122D8] ; Young and Middle-aged Education Department of Fujian Province Natural Science Foundation[JAT210261] ; Minnan Normal University[4206/L21829]
WOS研究方向	Fisheries ; Marine & Freshwater Biology
WOS类目	Fisheries ; Marine & Freshwater Biology
WOS记录号	WOS:001069762200001
出版者	ELSEVIER
WOS关键词	PACIFIC ABALONE ; HYBRIDIZATION ; EXPRESSION ; OYSTER
引用统计
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/181763
专题	实验海洋生物学重点实验室
通讯作者	Lin, Siheng
作者单位	1.Minnan Normal Univ, Dept Biol Sci & Biotechnol, Zhangzhou 363000, Fujian, Peoples R China 2.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Tang, Xueying,Li, Sisi,Zhuo, Ling,et al. Correlation study of SNP of glycogen degradation metabolism related genes and glycogen content in Haliotis discus hannai[J]. AQUACULTURE,2024,578:7.
APA	Tang, Xueying,Li, Sisi,Zhuo, Ling,Zhang, Qingya,Wu, Fucun,&Lin, Siheng.(2024).Correlation study of SNP of glycogen degradation metabolism related genes and glycogen content in Haliotis discus hannai.AQUACULTURE,578,7.
MLA	Tang, Xueying,et al."Correlation study of SNP of glycogen degradation metabolism related genes and glycogen content in Haliotis discus hannai".AQUACULTURE 578(2024):7.