Integrated application of transcriptomics and metabolomics provides insights into condition index difference mechanisms in the Pacific oyster (Crassostrea gigas)

doi:10.1016/j.ygeno.2022.110413

IOCAS-IR > 实验海洋生物学重点实验室

	Integrated application of transcriptomics and metabolomics provides insights into condition index difference mechanisms in the Pacific oyster (Crassostrea gigas)
	He, Xin 1,2,3,6; Wu, Fucun 1,2,5,6; Wang, Luping 1; Li, Li 1,4,5; Zhang, Guofan 1,2,5
	2022-07-01
发表期刊	GENOMICS
ISSN	0888-7543
卷号	114 期号:4 页码:13
通讯作者	Wu, Fucun(wufucun@qdio.ac.cn)
摘要	The condition index (CI) is an economically important tool for assessing the quality of oysters, such as the Pacific oyster Crassostrea gigas. However, little is known about the mechanisms that underlie differences in CI between different C. gigas populations. In this study, we integrated transcriptomic and metabolomic profiling to investigate the mechanisms that underlie the differences between high- and low-CI groups in one- and two-year-old populations of C. gigas. The results indicate that differences in CI were associated with the regulation of growth-related genes, the FoxO signaling pathway, and the complex regulation of carbohydrate, lipid, amino acid, and energy metabolism. Moreover, the mechanisms underlying these differences differed between the populations. This study is the first to elucidate the molecular and chemical mechanisms associated with CI, and the results will be helpful for breeding higher quality oysters.
关键词	Crassostrea gigas Condition index Transcriptomics Metabolomics Seafood
DOI	10.1016/j.ygeno.2022.110413
收录类别	SCI
语种	英语
资助项目	Strategic Priority Research Program of the Chinese Academy of Sciences[XDA24030105] ; Major Scientific and Technological Innovation Project of Shandong Province[2021LZGC029] ; Major Scientific and Technological Innovation Project of Shandong Province[2019JZZY010813] ; National Key R&D Program of China[2019YFD0900800] ; China Agriculture Research System of MOF and MARA[CARS-49]
WOS研究方向	Biotechnology & Applied Microbiology ; Genetics & Heredity
WOS类目	Biotechnology & Applied Microbiology ; Genetics & Heredity
WOS记录号	WOS:000833424100006
出版者	ACADEMIC PRESS INC ELSEVIER SCIENCE
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/179858
专题	实验海洋生物学重点实验室
通讯作者	Wu, Fucun
作者单位	1.Chinese Acad Sci, Ctr Ocean Megasci, Inst Oceanol, CAS & Shandong Prov Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Pilot Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 4.Pilot Natl Lab Marine Sci & Technol, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266237, Peoples R China 5.Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao 266071, Peoples R China 6.Chinese Acad Sci, Innovat Seed Design, Wuhan 430072, Peoples R China
第一作者单位	中国科学院海洋大科学研究中心
通讯作者单位	中国科学院海洋大科学研究中心
推荐引用方式 GB/T 7714	He, Xin,Wu, Fucun,Wang, Luping,et al. Integrated application of transcriptomics and metabolomics provides insights into condition index difference mechanisms in the Pacific oyster (Crassostrea gigas)[J]. GENOMICS,2022,114(4):13.
APA	He, Xin,Wu, Fucun,Wang, Luping,Li, Li,&Zhang, Guofan.(2022).Integrated application of transcriptomics and metabolomics provides insights into condition index difference mechanisms in the Pacific oyster (Crassostrea gigas).GENOMICS,114(4),13.
MLA	He, Xin,et al."Integrated application of transcriptomics and metabolomics provides insights into condition index difference mechanisms in the Pacific oyster (Crassostrea gigas)".GENOMICS 114.4(2022):13.