New Cytochalasin Derivatives from Deep-Sea Cold Seep-Derived Endozoic Fungus Curvularia verruculosa CS-129

doi:10.1002/cbdv.202200550

IOCAS-IR > 实验海洋生物学重点实验室

	New Cytochalasin Derivatives from Deep-Sea Cold Seep-Derived Endozoic Fungus Curvularia verruculosa CS-129
	Hu, Xue-Yi1,2,3 ; Li, Xiao-Ming 1,2; Yang, Sui-Qun 1,2; Wang, Bin-Gui1,2,3,4 ; Meng, Ling-Hong1,2
	2022-07-04
发表期刊	CHEMISTRY & BIODIVERSITY
ISSN	1612-1872
页码	7
通讯作者	Wang, Bin-Gui(wangbg@ms.qdio.ac.cn) ; Meng, Ling-Hong(menglh@ms.qdio.ac.cn)
摘要	Two new antimicrobial cytochalasin derivatives, 6 beta,7 beta-epoxydeoxaphomin C (1) and 12-hydroxydeoxaphomin C (2), a new natural occurring product 24-nor-cytochalasin B (3), together with two related known analogs (4-5) were isolated and identified from an endozoic fungus Curvularia verruculosa CS-129, isolated from the deep-sea squat lobster Shinkaia crosnieri which was collected in cold seep region of south China sea. The structures of new compounds were elucidated on the basis of detailed spectroscopic analysis and ECD calculation. The spectroscopic data of 24-nor-cytochalasin B (3) were reported for the first time. All compounds were tested for their antibacterial activities against human and aquatic pathogenic bacteria.
关键词	endozoic fungus Curvularia verruculosa marine natural products cytochalasin derivatives antimicrobial activity
DOI	10.1002/cbdv.202200550
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[U2006203] ; National Natural Science Foundation of China[41976090] ; Natural Science Foundation of Jiangsu Province[BK20201211] ; Senior User Project of RV KEXUE[KEXUE2020GZ02]
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
WOS类目	Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS记录号	WOS:000820399600001
出版者	WILEY-V C H VERLAG GMBH
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/179617
专题	实验海洋生物学重点实验室
通讯作者	Wang, Bin-Gui; Meng, Ling-Hong
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS & Shandong Prov Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Wenhai Rd 1, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Coll Marine Sci, Yuquan Rd 19 A, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Megasci, Nanhai Rd 7, Qingdao 266071, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所; 中国科学院海洋大科学研究中心
推荐引用方式 GB/T 7714	Hu, Xue-Yi,Li, Xiao-Ming,Yang, Sui-Qun,et al. New Cytochalasin Derivatives from Deep-Sea Cold Seep-Derived Endozoic Fungus Curvularia verruculosa CS-129[J]. CHEMISTRY & BIODIVERSITY,2022:7.
APA	Hu, Xue-Yi,Li, Xiao-Ming,Yang, Sui-Qun,Wang, Bin-Gui,&Meng, Ling-Hong.(2022).New Cytochalasin Derivatives from Deep-Sea Cold Seep-Derived Endozoic Fungus Curvularia verruculosa CS-129.CHEMISTRY & BIODIVERSITY,7.
MLA	Hu, Xue-Yi,et al."New Cytochalasin Derivatives from Deep-Sea Cold Seep-Derived Endozoic Fungus Curvularia verruculosa CS-129".CHEMISTRY & BIODIVERSITY (2022):7.