Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| Uncommon Polyketides from Penicillium steckii AS-324, a Marine Endozoic Fungus Isolated from Deep-Sea Coral in the Magellan Seamount | |
Hu, Xue-Yi1,2,3 ; Li, Xiao-Ming1,2; Wang, Bin-Gui1,2,3,4; Meng, Ling-Hong1,2,4
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| 2022-06-01 | |
| Source Publication | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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| Volume | 23Issue:11Pages:13 |
| Corresponding Author | Wang, Bin-Gui(wangbg@ms.qdio.ac.cn) ; Meng, Ling-Hong(menglh@ms.qdio.ac.cn) |
| Abstract | Four unusual steckwaic acids E-H (1-4), possessing a rarely described acrylic acid unit at C-4 (1-3) or a double bond between C-12 and C-13 (4) are reported for the first time, along with four new analogues (5-8) and two known congeners (9 and 10). They were purified from the organic extract of Penicillium steckii AS-324, an endozoic fungus obtained from a deep-sea coral Acanthogorgiidae sp., which was collected from the Magellan Seamount at a depth of 1458 m. Their structures were determined by the interpretation of NMR and mass spectroscopic data. The relative and absolute configurations were determined by NOESY correlations, X-ray crystallographic analysis, and ECD calculations. All compounds were tested for their antimicrobial activities against human- and aquatic-pathogenic bacteria and plant-related pathogenic fungi. |
| Keyword | marine endozoic fungus Penicillium steckii polyketide derivatives natural products structure elucidation biological activity |
| DOI | 10.3390/ijms23116332 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | National Natural Science Foundation of China[U2006203] ; National Natural Science Foundation of China[41976090] ; Natural Science Foundation of Jiangsu province[BK20201211] ; Natural Science Foundation of Jiangsu province[KEXUE2020GZ02] |
| WOS Research Area | Biochemistry & Molecular Biology ; Chemistry |
| WOS Subject | Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary |
| WOS ID | WOS:000808944800001 |
| Publisher | MDPI |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.qdio.ac.cn/handle/337002/179504 |
| Collection | 实验海洋生物学重点实验室 |
| Corresponding Author | Wang, Bin-Gui; Meng, Ling-Hong |
| Affiliation | 1.Chinese Acad Sci, Inst Oceanol, CAS & Shandong Prov Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Wenhai Rd 1, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Coll Marine Sci, Yuquan Rd 19A, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Mega Sci, Nanhai Rd 7, Qingdao 266071, Peoples R China |
| First Author Affilication | Institute of Oceanology, Chinese Academy of Sciences |
| Corresponding Author Affilication | Institute of Oceanology, Chinese Academy of Sciences |
| Recommended Citation GB/T 7714 | Hu, Xue-Yi,Li, Xiao-Ming,Wang, Bin-Gui,et al. Uncommon Polyketides from Penicillium steckii AS-324, a Marine Endozoic Fungus Isolated from Deep-Sea Coral in the Magellan Seamount[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2022,23(11):13. |
| APA | Hu, Xue-Yi,Li, Xiao-Ming,Wang, Bin-Gui,&Meng, Ling-Hong.(2022).Uncommon Polyketides from Penicillium steckii AS-324, a Marine Endozoic Fungus Isolated from Deep-Sea Coral in the Magellan Seamount.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,23(11),13. |
| MLA | Hu, Xue-Yi,et al."Uncommon Polyketides from Penicillium steckii AS-324, a Marine Endozoic Fungus Isolated from Deep-Sea Coral in the Magellan Seamount".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23.11(2022):13. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| ijms-23-06332-v2.pdf（3060KB） | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | View | |
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