Sesquiterpene and Sorbicillinoid Glycosides from the Endophytic Fungus Trichoderma longibrachiatum EN-586 Derived from the Marine Red Alga Laurencia obtusa

doi:10.3390/md20030177

IOCAS-IR > 实验海洋生物学重点实验室

	Sesquiterpene and Sorbicillinoid Glycosides from the Endophytic Fungus Trichoderma longibrachiatum EN-586 Derived from the Marine Red Alga Laurencia obtusa
	Wang, Ying1,2,3 ; Li, Xiao-Ming 1,2,4; Yang, Sui-Qun1,2,4 ; Zhang, Fan-Zhong1,2,3 ; Wang, Bin-Gui1,2,3,4 ; Li, Hong-Lei1,2,4 ; Meng, Ling-Hong1,2,3,4
	2022-03-01
发表期刊	MARINE DRUGS
卷号	20 期号:3 页码:11
通讯作者	Li, Hong-Lei(lihonglei@qdio.ac.cn) ; Meng, Ling-Hong(m8545303@163.com)
摘要	An unusual sesquiterpene glycoside trichoacorside A (1) and two novel sorbicillinoid glycosides sorbicillisides A (2) and B (3), together with a known compound sorbicillin (4), were isolated and identified from the culture extract of an endophytic fungus Trichoderma longibrachiatum EN-586, obtained from the marine red alga Laurencia obtusa. Trichoacorside A (1) is the first representative of a glucosamine-coupled acorane-type sesquiterpenoid. Their structures were elucidated based on detailed interpretation of NMR and mass spectroscopic data. The absolute configurations were determined by X-ray crystallographic analysis, chemical derivatization, and DP4+ probability analysis. The antimicrobial activities of compounds 1-4 against several human, aquatic, and plant pathogens were evaluated.
关键词	Trichoderma longibrachiatum sesquiterpene glycoside secondary metabolites antimicrobial activity
DOI	10.3390/md20030177
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[42176115] ; National Natural Science Foundation of China[42006079] ; Qingdao National Laboratory for Marine Science and Technology[YQ2018NO08] ; Qingdao National Laboratory for Marine Science and Technology[OF2019NO03] ; National Natural Science Foundation of Jiangsu province[BK20201211]
WOS研究方向	Pharmacology & Pharmacy
WOS类目	Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号	WOS:000774972100001
出版者	MDPI
引用统计	被引频次：9[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/178685
专题	实验海洋生物学重点实验室
通讯作者	Li, Hong-Lei; Meng, Ling-Hong
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS & Shandong Prov Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Wenhai Rd 1, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Yuquan Rd 19A, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Megasci, Nanhai Rd 7, Qingdao 266071, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所; 中国科学院海洋大科学研究中心
推荐引用方式 GB/T 7714	Wang, Ying,Li, Xiao-Ming,Yang, Sui-Qun,et al. Sesquiterpene and Sorbicillinoid Glycosides from the Endophytic Fungus Trichoderma longibrachiatum EN-586 Derived from the Marine Red Alga Laurencia obtusa[J]. MARINE DRUGS,2022,20(3):11.
APA	Wang, Ying.,Li, Xiao-Ming.,Yang, Sui-Qun.,Zhang, Fan-Zhong.,Wang, Bin-Gui.,...&Meng, Ling-Hong.(2022).Sesquiterpene and Sorbicillinoid Glycosides from the Endophytic Fungus Trichoderma longibrachiatum EN-586 Derived from the Marine Red Alga Laurencia obtusa.MARINE DRUGS,20(3),11.
MLA	Wang, Ying,et al."Sesquiterpene and Sorbicillinoid Glycosides from the Endophytic Fungus Trichoderma longibrachiatum EN-586 Derived from the Marine Red Alga Laurencia obtusa".MARINE DRUGS 20.3(2022):11.

条目包含的文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
marinedrugs-20-00177（2093KB）	期刊论文	出版稿	限制开放	CC BY-NC-SA	浏览