Assessing the Effect of Modified Clay on the Toxicity of Karenia mikimotoi Using Marine Medaka (Oryzias melastigma) as a Model Organism

doi:10.3390/toxics10030105

	Assessing the Effect of Modified Clay on the Toxicity of Karenia mikimotoi Using Marine Medaka (Oryzias melastigma) as a Model Organism
	Zhang, Peipei1,2,3,4 ; Song, Xiuxian1,2,3,4 ; Zhang, Yue 1,2; Zhu, Jianan 1,2,4; Shen, Huihui1,2,3,4 ; Yu, Zhiming1,2,3,4
	2022-03-01
发表期刊	TOXICS
卷号	10 期号:3 页码:19
通讯作者	Song, Xiuxian(songxx@qdio.ac.cn)
摘要	Blooms of the toxic dinoflagellate Karenia mikimotoi could threaten the survival of marine life, and modified clay (MC) is considered a promising method for the control of harmful algal blooms. Here, using marine medaka as the model organism, the toxicity of K. mikimotoi before and after MC disposal was investigated. The results showed that only a certain density of intact K. mikimotoi cells could cause obvious damage to fish gills and lead to rapid death. A systematic analysis of morphology, physiology, and molecular biology parameters revealed that the fish gills exhibited structural damage, oxidative damage, osmotic regulation impairment, immune response activation, and signal transduction enhancement. MC can flocculate K. mikimotoi rapidly in water and reduce its toxicity by reducing the density of intact algae cells and hemolytic toxicity. The results indicate that MC is an effective and safe method for controlling K. mikimotoi blooms.
关键词	modified clay Karenia mikimotoi harmful algal bloom marine medaka marine toxicity tests
DOI	10.3390/toxics10030105
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[41976148] ; Key R&D project of Shandong Province[2019JZZY010808] ; Taishan Program of Shandong Province of 2019
WOS研究方向	Environmental Sciences & Ecology ; Toxicology
WOS类目	Environmental Sciences ; Toxicology
WOS记录号	WOS:000776410900001
出版者	MDPI
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/178646
专题	海洋生态与环境科学重点实验室
通讯作者	Song, Xiuxian
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Ecol & Environm Sci, Qingdao 266000, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao 266000, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266000, Peoples R China
第一作者单位	中国科学院海洋研究所; 中国科学院海洋大科学研究中心
通讯作者单位	中国科学院海洋研究所; 中国科学院海洋大科学研究中心
推荐引用方式 GB/T 7714	Zhang, Peipei,Song, Xiuxian,Zhang, Yue,et al. Assessing the Effect of Modified Clay on the Toxicity of Karenia mikimotoi Using Marine Medaka (Oryzias melastigma) as a Model Organism[J]. TOXICS,2022,10(3):19.
APA	Zhang, Peipei,Song, Xiuxian,Zhang, Yue,Zhu, Jianan,Shen, Huihui,&Yu, Zhiming.(2022).Assessing the Effect of Modified Clay on the Toxicity of Karenia mikimotoi Using Marine Medaka (Oryzias melastigma) as a Model Organism.TOXICS,10(3),19.
MLA	Zhang, Peipei,et al."Assessing the Effect of Modified Clay on the Toxicity of Karenia mikimotoi Using Marine Medaka (Oryzias melastigma) as a Model Organism".TOXICS 10.3(2022):19.

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