Multifunctional ratiometric fluorescent sensing platform constructed by grafting various response groups on carbon dots with bromine active site for biosensing and bioimaging

doi:10.1016/j.snb.2022.131376

	Multifunctional ratiometric fluorescent sensing platform constructed by grafting various response groups on carbon dots with bromine active site for biosensing and bioimaging
	Zou, Guang-Yue 1; Guo, Lan 1; Chen, Shuai 1; Liu, Na-Zhen 2; Yu, Yong-Liang 1
	2022-04-15
发表期刊	SENSORS AND ACTUATORS B-CHEMICAL
卷号	357 页码:10
通讯作者	Chen, Shuai(chenshuai@mail.neu.edu.cn) ; Liu, Na-Zhen(liunazhen@qdio.ac.cn)
摘要	Multifunctional sensing platform with the advantages of simplicity, convenience and efficiency is critical to the improvement of application in biosensing and bioimaging. However, the lack of easily modified scaffold materials seriously hinders its various responsive sensing development. To solve this issue, a novel kind of carbon dots (namely rCDs) with easily modified bromine substitution site was developed by one-step solvothermal treatment of citric acid, ethylenediamine and 4-bromo-1,8-naphthalic anhydride. Benefiting from the maintained structure of naphthalimide structure with bromine substitution site to contribute responsive yellow-green fluorescence emission and the stable blue fluorescence emission from citric acid and ethylenediamine, dual emissive ratiometric sensors based on rCDs could be conveniently fabricated by avoiding the combination of two components with distinct emission wavelength together. As proof, three ratiometric fluorescent probes for sensing formaldehyde (rCDs-FA), HSO3- (rCDs-HSO3-) and pH (rCDs-pH) featuring high stability, selectivity and biocompatibility were simply prepared. Moreover, the as-obtained probes were successfully applied to monitor dynamic variations of formaldehyde, HSO3- and pH changes in living cells. Taken together, the established multifunctional ratiometric fluorescent sensing platform could be simply and effectively regulated through changing the grafted response groups. This work would provide a universal method to design more biosensing or bioimaging platforms by adjusting response groups in the future.
关键词	Carbon dots Ratiometric fluorescence sensing Cell imaging Formaldehyde HSO3- pH
DOI	10.1016/j.snb.2022.131376
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[21922402] ; National Natural Science Foundation of China[21874017] ; National Natural Science Foundation of China[21727811] ; Fundamental Research Funds for the Central Universities[N2005027]
WOS研究方向	Chemistry ; Electrochemistry ; Instruments & Instrumentation
WOS类目	Chemistry, Analytical ; Electrochemistry ; Instruments & Instrumentation
WOS记录号	WOS:000744545000006
出版者	ELSEVIER SCIENCE SA
引用统计	被引频次：14[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/177724
专题	海洋环境腐蚀与生物污损重点实验室
通讯作者	Chen, Shuai; Liu, Na-Zhen
作者单位	1.Northeastern Univ, Coll Sci, Res Ctr Analyt Sci, Dept Chem, Shenyang 110819, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Environm Corros & Biofouling, Qingdao 266071, Peoples R China
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Zou, Guang-Yue,Guo, Lan,Chen, Shuai,et al. Multifunctional ratiometric fluorescent sensing platform constructed by grafting various response groups on carbon dots with bromine active site for biosensing and bioimaging[J]. SENSORS AND ACTUATORS B-CHEMICAL,2022,357:10.
APA	Zou, Guang-Yue,Guo, Lan,Chen, Shuai,Liu, Na-Zhen,&Yu, Yong-Liang.(2022).Multifunctional ratiometric fluorescent sensing platform constructed by grafting various response groups on carbon dots with bromine active site for biosensing and bioimaging.SENSORS AND ACTUATORS B-CHEMICAL,357,10.
MLA	Zou, Guang-Yue,et al."Multifunctional ratiometric fluorescent sensing platform constructed by grafting various response groups on carbon dots with bromine active site for biosensing and bioimaging".SENSORS AND ACTUATORS B-CHEMICAL 357(2022):10.

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