Glycogen Synthase Kinase 3 Gene Is Important in Growth and Molting of the Pacific White Shrimp Litopenaeus vannamei

doi:10.3389/fmars.2021.681966

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	Glycogen Synthase Kinase 3 Gene Is Important in Growth and Molting of the Pacific White Shrimp Litopenaeus vannamei
	Pang, Ying1,2,3 ; Zhang, Xiaojun 1,2,3; Yuan, Jianbo 1,2,3; Zhang, Xiaoxi1,2 ; Su, Manwen1,3 ; Li, Fuhua 1,2,3
	2021-06-24
发表期刊	FRONTIERS IN MARINE SCIENCE
卷号	8 页码:12
通讯作者	Zhang, Xiaojun(xjzhang@qdio.ac.cn)
摘要	Glycogen synthase kinase 3 (GSK3) is a vital multifunctional molecule that is widely distributed in invertebrates and vertebrates. GSK3 is a highly conserved serine/threonine (Ser/Thr) protein kinase, which plays an important role in insulin, Wnt, and various signaling pathways. In this study, a GSK3 gene were identified in the genome of the Pacific white shrimp, Litopenaeus vannamei, and analyzed its gene structure, phylogeny, and expression profiles. The deduced LvGSK3 protein contains a highly conserved Ser/Thr protein kinase catalytic (S_TKc) domain, the LvGSK3 gene exhibited high expression in different early developmental stages, most adult tissues, and premolting stages. RNA interference of LvGSK3 significantly retarded the increment of body weight and affected the expressions of molting-related genes compared with control groups. These results will improve our understanding of the conserved structure and functions of the LvGSK3 gene and show potential applications of shrimp growth.
关键词	glycogen synthase kinase 3 Litopenaeus vannamei growth molting structure and function
DOI	10.3389/fmars.2021.681966
收录类别	SCI
语种	英语
资助项目	National Key R&D Program of China[2018YFD0900404] ; National Key R&D Program of China[2018YFD0900103] ; National Natural Sciences Foundation of China[31972782] ; National Natural Sciences Foundation of China[41876167] ; National Natural Sciences Foundation of China[31672632] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDA24030105]
WOS研究方向	Environmental Sciences & Ecology ; Marine & Freshwater Biology
WOS类目	Environmental Sciences ; Marine & Freshwater Biology
WOS记录号	WOS:000668965900001
出版者	FRONTIERS MEDIA SA
引用统计	被引频次：4[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/176964
专题	实验海洋生物学重点实验室
通讯作者	Zhang, Xiaojun
作者单位	1.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, CAS & Shandong Prov Key Lab Expt Marine Biol, Qingdao, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China 3.Univ Chinese Acad Sci, Coll Earth Sci, Beijing, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Pang, Ying,Zhang, Xiaojun,Yuan, Jianbo,et al. Glycogen Synthase Kinase 3 Gene Is Important in Growth and Molting of the Pacific White Shrimp Litopenaeus vannamei[J]. FRONTIERS IN MARINE SCIENCE,2021,8:12.
APA	Pang, Ying,Zhang, Xiaojun,Yuan, Jianbo,Zhang, Xiaoxi,Su, Manwen,&Li, Fuhua.(2021).Glycogen Synthase Kinase 3 Gene Is Important in Growth and Molting of the Pacific White Shrimp Litopenaeus vannamei.FRONTIERS IN MARINE SCIENCE,8,12.
MLA	Pang, Ying,et al."Glycogen Synthase Kinase 3 Gene Is Important in Growth and Molting of the Pacific White Shrimp Litopenaeus vannamei".FRONTIERS IN MARINE SCIENCE 8(2021):12.

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