IOCAS-IR
The Cardamine enshiensis genome reveals whole genome duplication and insight into selenium hyperaccumulation and tolerance
Huang, Chuying1,2; Ying, Hongqin3; Yang, Xibiao4; Gao, Yuan5; Li, Tuo1,2; Wu, Bo1,2; Ren, Meng6,7; Zhang, Zixiong1,2; Ding, Jun1,2; Gao, Jianhua8; Wen, Dan9; Ye, Xingzhi8; Liu, Ling10; Wang, Huan10; Sun, Guogen1,2; Zou, Yi1,2; Chen, Nansheng11,12; Wang, Li1,2
2021-08-10
Source PublicationCELL DISCOVERY
Volume7Issue:1Pages:14
Corresponding AuthorHuang, Chuying(huangchuying2008@126.com)
AbstractCardamine enshiensis is a well-known selenium (Se)-hyperaccumulating plant. Se is an essential trace element associated with many health benefits. Despite its critical importance, genomic information of this species is limited. Here, we report a chromosome-level genome assembly of C. enshiensis, which consists of 443.4 Mb in 16 chromosomes with a scaffold N50 of 24 Mb. To elucidate the mechanism of Se tolerance and hyperaccumulation in C. enshiensis, we generated and analyzed a dataset encompassing genomes, transcriptomes, and metabolomes. The results reveal that flavonoid, glutathione, and lignin biosynthetic pathways may play important roles in protecting C. enshiensis from stress induced by Se. Hi-C analysis of chromatin interaction patterns showed that the chromatin of C. enshiensis is partitioned into A and B compartments, and strong interactions between the two telomeres of each chromosome were correlated with histone modifications, epigenetic markers, DNA methylation, and RNA abundance. Se supplementation could affect the 3D chromatin architecture of C. enshiensis at the compartment level. Genes with compartment changes after Se treatment were involved in selenocompound metabolism, and genes in regions with topologically associated domain insulation participated in cellular responses to Se, Se binding, and flavonoid biosynthesis. This multiomics research provides molecular insight into the mechanism underlying Se tolerance and hyperaccumulation in C. enshiensis.
DOI10.1038/s41421-021-00286-x
Indexed BySCI
Language英语
Funding ProjectNational Natural Science Foundation of China[81660503]
WOS Research AreaCell Biology
WOS SubjectCell Biology
WOS IDWOS:000685106500002
PublisherSPRINGERNATURE
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/176032
Collection中国科学院海洋研究所
Corresponding AuthorHuang, Chuying
Affiliation1.Hubei Minzu Univ Affiliated Enshi Clin, Med Sch, Cent Hosp Enshi Tujia & Miao Autonomous Prefectur, Enshi, Hubei, Peoples R China
2.Hubei Selenium & Human Hlth Inst, Enshi, Hubei, Peoples R China
3.Enshi Autonomous Prefecture Acad Agr Sci, Hubei Selenium Ind Technol Res Inst, Enshi, Hubei, Peoples R China
4.Sichuan Univ, West China Hosp, Dept Radiol, Chengdu, Sichuan, Peoples R China
5.Univ Gothenburg, Dept Chem & Mol Biol, SE-40530 Gothenburg, Sweden
6.East China Normal Univ, Ctr Bioinformat & Computat Biol, Sch Life Sci, Shanghai, Peoples R China
7.East China Normal Univ, Inst Biomed Sci, Sch Life Sci, Shanghai, Peoples R China
8.Enshi Autonomous Prefecture Acad Agr Sci, South China Potato Res Ctr, Enshi, Hubei, Peoples R China
9.Bur Agr & Rural Affairs Enshi Tujia & Miao Autono, Enshi, Hubei, Peoples R China
10.Wuhan Frasergen Bioinformat Co Ltd, Wuhan, Hubei, Peoples R China
11.Chinese Acad Sci, Inst Oceanol, Qingdao, Shandong, Peoples R China
12.Simon Fraser Univ, Dept Mol Biol & Biochem, Burnaby, BC, Canada
Recommended Citation
GB/T 7714
Huang, Chuying,Ying, Hongqin,Yang, Xibiao,et al. The Cardamine enshiensis genome reveals whole genome duplication and insight into selenium hyperaccumulation and tolerance[J]. CELL DISCOVERY,2021,7(1):14.
APA Huang, Chuying.,Ying, Hongqin.,Yang, Xibiao.,Gao, Yuan.,Li, Tuo.,...&Wang, Li.(2021).The Cardamine enshiensis genome reveals whole genome duplication and insight into selenium hyperaccumulation and tolerance.CELL DISCOVERY,7(1),14.
MLA Huang, Chuying,et al."The Cardamine enshiensis genome reveals whole genome duplication and insight into selenium hyperaccumulation and tolerance".CELL DISCOVERY 7.1(2021):14.
Files in This Item:
File Name/Size DocType Version Access License
s41421-021-00286-x.p(1992KB)期刊论文出版稿延迟开放CC BY-NC-SAView 2023-7-1后可获取
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Huang, Chuying]'s Articles
[Ying, Hongqin]'s Articles
[Yang, Xibiao]'s Articles
Baidu academic
Similar articles in Baidu academic
[Huang, Chuying]'s Articles
[Ying, Hongqin]'s Articles
[Yang, Xibiao]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Huang, Chuying]'s Articles
[Ying, Hongqin]'s Articles
[Yang, Xibiao]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: s41421-021-00286-x.pdf
Format: Adobe PDF
This file does not support browsing at this time
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.