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一种原核重组表达的栉孔扇贝CfSRCR-2基因及其制备和应用
宋林生; 刘瑞; 王玲玲; 邱丽梅; 张峘
2014-03-19
Rights Holder中国科学院海洋研究所.
Date Available2014-03-19
Subtype发明
Abstract本发明属于基因工程领域,具体的说是一种原核重组表达的栉孔扇贝CfSRCR-2基因及其制备和应用。CfSRCR-2基因的重组蛋白为序列表SEQ?ID?NO.1中氨基酸序列所示。具体构建采用通过PCR技术扩增栉孔扇贝CfSRCR-2分子基因的cDNA全长,并对其编码区进行原核重组表达。本发明提供的栉孔扇贝CfSRCR-2基因含有SRCR结构域的活性分子。该蛋白不仅可以结合乙酰化的低密度脂蛋白和甘露糖,是一种重要的免疫受体分子,而且能够直接抑制革兰氏阴性菌的生长,从而起到免疫效应分子的作用,可见本发明蛋白可作为较好的免疫增强剂候选分子。
Keyword一种原核重组表达的栉孔扇贝cfsrcr?2基因 其特征在于:cfsrcr?2基因的重组蛋白为序列表seq?id?no.1中氨基酸序列所示。
Application Date2013-12-05
Patent NumberCN201310655247.2
Language中文
Status公开
Application NumberCN201310655247.2
Document Type专利
Identifierhttp://ir.qdio.ac.cn/handle/337002/17213
Collection实验海洋生物学重点实验室
Recommended Citation
GB/T 7714
宋林生,刘瑞,王玲玲,等. 一种原核重组表达的栉孔扇贝CfSRCR-2基因及其制备和应用. CN201310655247.2[P]. 2014-03-19.
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