Genome-Wide Transcriptional Responses of Marine Nematode Litoditis marina to Hyposaline and Hypersaline Stresses

doi:10.3389/fphys.2021.672099

IOCAS-IR > 实验海洋生物学重点实验室

	Genome-Wide Transcriptional Responses of Marine Nematode Litoditis marina to Hyposaline and Hypersaline Stresses
	Xie, Yusu 1,2,3,4; Zhang, Pengchi 1,2,3,4,5; Zhang, Liusuo 1,2,3,4
	2021-05-04
发表期刊	FRONTIERS IN PHYSIOLOGY
ISSN	1664-042X
卷号	12 页码:15
通讯作者	Zhang, Liusuo(lzhang@qdio.ac.cn)
摘要	Maintenance of osmotic homeostasis is essential for all organisms, especially for marine animals in the ocean with 3% salinity or higher. However, the underlying molecular mechanisms that how marine animals adapt to high salinity environment compared to their terrestrial relatives, remain elusive. Here, we investigated marine animal's genome-wide transcriptional responses to salinity stresses using an emerging marine nematode model Litoditis marina. We found that the transthyretin-like family genes were significantly increased in both hyposaline and hypersaline conditions, while multiple neurotransmitter receptor and ion transporter genes were down-regulated in both conditions, suggesting the existence of conserved strategies for response to stressful salinity environments in L. marina. Unsaturated fatty acids biosynthesis related genes, neuronal related tubulins and intraflagellar transport genes were specifically up-regulated in hyposaline treated worms. By contrast, cuticle related collagen genes were enriched and up-regulated for hypersaline response. Given a wide range of salinity tolerance of the marine nematodes, this study and further genetic analysis of key gene(s) of osmoregulation in L. marina will likely provide important insights into biological evolution and environmental adaptation mechanisms in nematodes and other invertebrate animals in general.
关键词	salinity stress marine nematode Litoditis marina hypersaline gene expression hyposaline
DOI	10.3389/fphys.2021.672099
收录类别	SCI
语种	英语
资助项目	National Key R&D Program of China[2018YFD0901301] ; National Natural Science Foundation of China[41806169] ; Qingdao National Laboratory for Marine Science and Technology[YQ2018NO10] ; Key deployment project of Centre for Ocean Mega-Research of Science, Chinese Academy of Sciences ; Talents from overseas Program, IOCAS of the Chinese Academy of Sciences ; Qingdao Innovation Leadership Program[16-8-3-19-zhc]
WOS研究方向	Physiology
WOS类目	Physiology
WOS记录号	WOS:000651402900001
出版者	FRONTIERS MEDIA SA
引用统计	被引频次：7[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/171005
专题	实验海洋生物学重点实验室
通讯作者	Zhang, Liusuo
作者单位	1.Chinese Acad Sci, Qingdao, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Shandong Prov Key Lab Expt Marine Biol, Qingdao, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao, Peoples R China 5.Univ Chinese Acad Sci, Beijing, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Xie, Yusu,Zhang, Pengchi,Zhang, Liusuo. Genome-Wide Transcriptional Responses of Marine Nematode Litoditis marina to Hyposaline and Hypersaline Stresses[J]. FRONTIERS IN PHYSIOLOGY,2021,12:15.
APA	Xie, Yusu,Zhang, Pengchi,&Zhang, Liusuo.(2021).Genome-Wide Transcriptional Responses of Marine Nematode Litoditis marina to Hyposaline and Hypersaline Stresses.FRONTIERS IN PHYSIOLOGY,12,15.
MLA	Xie, Yusu,et al."Genome-Wide Transcriptional Responses of Marine Nematode Litoditis marina to Hyposaline and Hypersaline Stresses".FRONTIERS IN PHYSIOLOGY 12(2021):15.

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