Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| Characterization of Different Salt Forms of Chitooligosaccharides and Their Effects on Nitric Oxide Secretion by Macrophages | |
Xing, Ronge1,2,3 ; Xu, Chaojie1,2,3,4; Gao, Kun1,2,3,4; Yang, Haoyue1,2,3; Liu, Yongliang3; Fan, Zhaoqian1,2,3; Liu, Song1,2,3; Qin, Yukun1,2,3; Yu, Huahua1,2,3; Li, Pengcheng1,2,3
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| 2021-05-01 | |
| Source Publication | MOLECULES
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| Volume | 26Issue:9Pages:17 |
| Corresponding Author | Xing, Ronge(xingronge@qdio.ac.cn) |
| Abstract | In this paper, chitooligosaccharides in different salt forms, such as chitooligosaccharide lactate, citrate, adipate, etc., were prepared by the microwave method. They were characterized by SEM, FTIR, NMR, etc., and the nitric oxide (NO) expression was determined in RAW 264.7 cells. The results showed that pure chitooligosaccharide was an irregular spherical shape with rough surface, and its different salt type products are amorphous solid with different honeycomb sizes. In addition to the characteristic absorption peaks of chitooligosaccharides, in FTIR, the characteristic absorption of carboxyl group, methylene group, and aromatic group in corresponding acid appeared. The characteristic absorption peaks of carbon in carboxyl group, hydrogen and carbon in methyl, methylene group, and aromatic group in corresponding acid also appeared in NMR. Therefore, the sugar ring structure and linking mode of chitooligosaccharides did not change after salt formation of chitooligosaccharides. Different salt chitooligosaccharides are completely different in promoting NO secretion by macrophages, and pure chitooligosaccharides are the best. |
| Keyword | pure chitooligosaccharides chitooligosaccharides salts characterization promoting NO production |
| DOI | 10.3390/molecules26092563 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | Key deployment projects of the Marine Science Research Center of Chinese Academy of Sciences[COMS2020J04] ; Key Research and Development Program of Shandong Province[2019YYSP028] |
| WOS Research Area | Biochemistry & Molecular Biology ; Chemistry |
| WOS Subject | Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary |
| WOS ID | WOS:000650682300001 |
| Publisher | MDPI |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.qdio.ac.cn/handle/337002/170884 |
| Collection | 实验海洋生物学重点实验室 |
| Corresponding Author | Xing, Ronge |
| Affiliation | 1.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, CAS, 7 Nanhai Rd, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, Shandong Prov Key Lab Expt Marine Biol, 7 Nanhai Rd, Qingdao 266071, Peoples R China 3.Pilot Natl Lab Marine Sci & Technol Qingdao, Lab Marine Drugs & Bioprod, 1 Wenhai Rd, Qingdao 266237, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| First Author Affilication | Institute of Oceanology, Chinese Academy of Sciences |
| Corresponding Author Affilication | Institute of Oceanology, Chinese Academy of Sciences |
| Recommended Citation GB/T 7714 | Xing, Ronge,Xu, Chaojie,Gao, Kun,et al. Characterization of Different Salt Forms of Chitooligosaccharides and Their Effects on Nitric Oxide Secretion by Macrophages[J]. MOLECULES,2021,26(9):17. |
| APA | Xing, Ronge.,Xu, Chaojie.,Gao, Kun.,Yang, Haoyue.,Liu, Yongliang.,...&Li, Pengcheng.(2021).Characterization of Different Salt Forms of Chitooligosaccharides and Their Effects on Nitric Oxide Secretion by Macrophages.MOLECULES,26(9),17. |
| MLA | Xing, Ronge,et al."Characterization of Different Salt Forms of Chitooligosaccharides and Their Effects on Nitric Oxide Secretion by Macrophages".MOLECULES 26.9(2021):17. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| molecules-26-02563.p（6181KB） | 期刊论文 | 出版稿 | 延迟开放 | CC BY-NC-SA | View 2023-7-1后可获取 | |
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