The Chinese mitten crab genome provides insights into adaptive plasticity and developmental regulation

doi:10.1038/s41467-021-22604-3

IOCAS-IR > 实验海洋生物学重点实验室

	The Chinese mitten crab genome provides insights into adaptive plasticity and developmental regulation
	Cui, Zhaoxia 1,2,3; Liu, Yuan 2,3,4; Yuan, Jianbo 2,3,4; Zhang, Xiaojun 2,3,4; Ventura, Tomer 5; Ma, Ka Yan 6; Sun, Shuai 7; Song, Chengwen2 ; Zhan, Dongliang 8; Yang, Yanan 1; Liu, Hourong 2; Fan, Guangyi 7; Cai, Qingle 8; Du, Jing 2; Qin, Jing 6,9; Shi, Chengcheng 7; Hao, Shijie 7; Fitzgibbon, Quinn P.10; Smith, Gregory G.10; Xiang, Jianhai2,3,4 ; Chan, Tin-Yam 11,12; Hui, Min 2,3,4; Bao, Chenchang 1; Li, Fuhua 2,3,4; Chu, Ka Hou 6
	2021-04-22
发表期刊	NATURE COMMUNICATIONS
ISSN	2041-1723
卷号	12 期号:1 页码:13
通讯作者	Cui, Zhaoxia(cuizhaoxia@nbu.edu.cn) ; Li, Fuhua(fhli@qdio.ac.cn) ; Chu, Ka Hou(kahouchu@cuhk.edu.hk)
摘要	Brachyurans, or crabs, are of commercial and ecological importance, but limited genomic resources exist. Here the authors present a chromosome-level genome and expression data for the Chinese mitten crab, to shed light on the biology of this group. The infraorder Brachyura (true or short-tailed crabs) represents a successful group of marine invertebrates yet with limited genomic resources. Here we report a chromosome-anchored reference genome and transcriptomes of the Chinese mitten crab Eriocheir sinensis, a catadromous crab and invasive species with wide environmental tolerance, strong osmoregulatory capacity and high fertility. We show the expansion of specific gene families in the crab, including F-ATPase, which enhances our knowledge on the adaptive plasticity of this successful invasive species. Our analysis of spatio-temporal transcriptomes and the genome of E. sinensis and other decapods shows that brachyurization development is associated with down-regulation of Hox genes at the megalopa stage when tail shortening occurs. A better understanding of the molecular mechanism regulating sexual development is achieved by integrated analysis of multiple omics. These genomic resources significantly expand the gene repertoire of Brachyura, and provide insights into the biology of this group, and Crustacea in general.
DOI	10.1038/s41467-021-22604-3
收录类别	SCI
语种	英语
资助项目	National Key R&D Program of China[2018YFD0900303] ; National Natural Science Foundation of China[32072964] ; Ten Thousand Talents Program ; Scientific and Technological Innovation Project of Qingdao National Laboratory for Marine Science and Technology[2015ASKJ02] ; Collaborative Research Fund from the Research Grants Council, Hong Kong Special Administrative Region, China[C4042-14G] ; Ministry of Science and Technology, Taiwan ; Center of Excellence for the Oceans, National Taiwan Ocean University
WOS研究方向	Science & Technology - Other Topics
WOS类目	Multidisciplinary Sciences
WOS记录号	WOS:000642744500028
出版者	NATURE RESEARCH
引用统计	被引频次：35[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/170818
专题	实验海洋生物学重点实验室
通讯作者	Cui, Zhaoxia; Li, Fuhua; Chu, Ka Hou
作者单位	1.Ningbo Univ, Sch Marine Sci, Ningbo, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao, Peoples R China 5.Univ Sunshine Coast, Sch Sci & Engn, Sippy Downs, Qld, Australia 6.Chinese Univ Hong Kong, Sch Life Sci, Simon FS Li Marine Sci Lab, Shatin, Hong Kong, Peoples R China 7.BGI Shenzhen, BGI Qingdao, Qingdao, Peoples R China 8.IGENE, Hangzhou, Peoples R China 9.Sun Yat Sen Univ, Sch Pharmaceut Sci Shenzhen, Guangzhou, Peoples R China 10.Univ Tasmania, Inst Marine & Antarctic Studies, Hobart, Tas, Australia 11.Natl Taiwan Ocean Univ, Inst Marine Biol, Keelung, Taiwan 12.Natl Taiwan Ocean Univ, Ctr Excellence Oceans, Keelung, Taiwan
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Cui, Zhaoxia,Liu, Yuan,Yuan, Jianbo,et al. The Chinese mitten crab genome provides insights into adaptive plasticity and developmental regulation[J]. NATURE COMMUNICATIONS,2021,12(1):13.
APA	Cui, Zhaoxia.,Liu, Yuan.,Yuan, Jianbo.,Zhang, Xiaojun.,Ventura, Tomer.,...&Chu, Ka Hou.(2021).The Chinese mitten crab genome provides insights into adaptive plasticity and developmental regulation.NATURE COMMUNICATIONS,12(1),13.
MLA	Cui, Zhaoxia,et al."The Chinese mitten crab genome provides insights into adaptive plasticity and developmental regulation".NATURE COMMUNICATIONS 12.1(2021):13.

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