Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| Secondary Metabolites with Agricultural Antagonistic Potentials from Beauveria felina, a Marine-Derived Entomopathogenic Fungus | |
Du, Feng-Yu1,2,3; Li, Xiao-Ming2,3; Sun, Ze-Chun4; Meng, Ling-Hong2,3 ; Wang, Bin-Gui2,3,5
| |
| 2020-12-16 | |
| Source Publication | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
 |
| ISSN | 0021-8561 |
| Volume | 68Issue:50Pages:14824-14831 |
| Corresponding Author | Wang, Bin-Gui(wangbg@ms.qdio.ac.cn) |
| Abstract | Soil-borne pathogens and weeds could synergistically affect vegetable growth and result in serious losses. The investigation of antagonistic metabolites from a marine-derived entomopathogenic fungus, Beauveria felina, obtained polyhydroxy steroid (1), tricyclic diterpenoid (2), isaridin (3), and destruxin cyclodepsipeptides (4-6). The structures and absolute configurations of new 1-3 were elucidated by extensive spectroscopic and X-ray crystallographic analyses, as well as electronic circular dichroism (ECD) calculations. Compounds 1 and 2 showed antifungal activities against carbendazim-resistant strains of Botrytis cinerea, with the minimum inhibitory concentration (MIC) values ranging from 16 to 32 mu g/mL, which were significantly better than those of carbendazim (MIC = 256 mu g/mL). Compound 5 exhibited significant antagonistic activity against the radicle growth of Amaranthus retroflexus seedlings, which was almost identical to that of the positive control (2,4-dichlorophenoxyacetic acid). The structure-activity differences of 4-6 suggested that the CI atom in HMPA(1) and beta-Me in Pro(2) should be the key factors to their herbicidal activities. Besides, compounds 3-6 showed moderate nematicidal activities against Meloidogyne incognita. These antagonistic effects of 1-6 were first reported and further revealed the synergistically antagonistic potential of B. felina to be developed into the biopesticide. |
| Keyword | Beauveria felina agricultural antagonistic potential secondary metabolites antifungal activity herbicidal activity |
| DOI | 10.1021/acs.jafc.0c05696 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | Natural Science Foundation of China[31270104] ; NSFCShandong Joint Fund for Marine Science Research Centers[U1606403] ; Taishan Scholar project from Shandong province[ts201511060] |
| WOS Research Area | Agriculture ; Chemistry ; Food Science & Technology |
| WOS Subject | Agriculture, Multidisciplinary ; Chemistry, Applied ; Food Science & Technology |
| WOS ID | WOS:000600204700010 |
| Publisher | AMER CHEMICAL SOC |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.qdio.ac.cn/handle/337002/169496 |
| Collection | 实验海洋生物学重点实验室 |
| Corresponding Author | Wang, Bin-Gui |
| Affiliation | 1.Qingdao Agr Univ, Coll Chem & Pharmaceut Sci, Qingdao 266109, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 3.Chinese Acad Sci, Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Peoples R China 4.Qingdao Agr Univ, Coll Chem & Pharm, Qingdao 266109, Peoples R China 5.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China |
| First Author Affilication | Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences |
| Corresponding Author Affilication | Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences; Center for Ocean Mega-Science, Chinese Academy of Sciences |
| Recommended Citation GB/T 7714 | Du, Feng-Yu,Li, Xiao-Ming,Sun, Ze-Chun,et al. Secondary Metabolites with Agricultural Antagonistic Potentials from Beauveria felina, a Marine-Derived Entomopathogenic Fungus[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2020,68(50):14824-14831. |
| APA | Du, Feng-Yu,Li, Xiao-Ming,Sun, Ze-Chun,Meng, Ling-Hong,&Wang, Bin-Gui.(2020).Secondary Metabolites with Agricultural Antagonistic Potentials from Beauveria felina, a Marine-Derived Entomopathogenic Fungus.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,68(50),14824-14831. |
| MLA | Du, Feng-Yu,et al."Secondary Metabolites with Agricultural Antagonistic Potentials from Beauveria felina, a Marine-Derived Entomopathogenic Fungus".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 68.50(2020):14824-14831. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| acs.jafc.0c05696.pdf（3509KB） | 期刊论文 | 出版稿 | 延迟开放 | CC BY-NC-SA | View 2023-7-1后可获取 | |
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment