Transcriptional changes of Pacific oyster Crassostrea gigas reveal essential role of calcium signal pathway in response to CO2-driven acidification

doi:10.1016/j.scitotenv.2020.140177

IOCAS-IR > 实验海洋生物学重点实验室

	Transcriptional changes of Pacific oyster Crassostrea gigas reveal essential role of calcium signal pathway in response to CO2-driven acidification
	Wang, Xiudan1,2 ; Wang, Mengqiang1 ; Wang, Weilin3,4 ; Liu, Zhaoqun3,4 ; Xu, Jiachao1 ; Jia, Zhihao 1; Chen, Hao1 ; Qiu, Limei 1; Lv, Zhao 1; Wang, Lingling 3,4,5; Song, Linsheng 3,4,5
	2020-11-01
发表期刊	SCIENCE OF THE TOTAL ENVIRONMENT
ISSN	0048-9697
卷号	741 页码:12
通讯作者	Song, Linsheng(lshsong@dlou.edu.cn)
摘要	There is increasing evidence that ocean acidification (OA) has a significant impact on marine organisms. How ever, the ability of most marine organisms to acclimate to OA and the underlying mechanisms are still not well understood. In the present study, whole transcriptome analysis was performed to compare the impacts of short(7 days, named as short group) and long(60 days, named as long group) term CO2 exposure (pH 7.50) on Pacific oyster Crassostrea gigas. The responses of C. gigas to shortand long-term CO2 exposure shared common mechanisms in metabolism, membrane-associated transportation and binding processes. Long-term CO2 exposure induced significant expression of genes involved in DNA or RNA binding, indicating the activated transcription after long-term CO2 exposure. Oysters in the short-term group underwent significant intracellular calcium variation and oxidative stress. In contrast, the intracellular calcium, ROS level in hemocytes and H2O2 in serum recovered to normal levels after long-term CO2 exposure, suggesting the compensation of physiological status and mutual interplay between calcium and oxidative level. The compensation was supported by the upregulation of a series of calcium binding proteins (CBPs) and calmodulins (CaMs) related signal pathway. The results provided valuable information to understand the molecular mechanism underlying the responses of Pacific oyster to the acidified ocean and might have implications for predicting the possible effects of global climate changes on oyster aquaculture. (c) 2020 Elsevier B.V. All rights reserved.
关键词	Transcriptome Crassostrea gigas Calcium signal CO2-driven acidification
DOI	10.1016/j.scitotenv.2020.140177
收录类别	SCI
语种	英语
资助项目	National Key RD Program[2018YFD0900606] ; National Science Foundation of China[U1706204] ; National Science Foundation of China[31800414] ; National Science Foundation of China[41961124009] ; Key Laboratory of Experimental Marine Biology, Chinese Academy of Sciences[KF2018NO1] ; earmarked fund from Modern Agro-industry Technology Research System[CARS-49] ; Fund for Outstanding Talents and Innovative Team of Agricultural Scientific Research ; AoShan Talents Cultivation Program ; Qingdao National Laboratory for Marine Science and Technology[2017ASTCP-OS13] ; Shandong Province Natural Science Foundation[ZR2019BC040]
WOS研究方向	Environmental Sciences & Ecology
WOS类目	Environmental Sciences
WOS记录号	WOS:000568815900001
出版者	ELSEVIER
引用统计	被引频次：25[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/168793
专题	实验海洋生物学重点实验室
通讯作者	Song, Linsheng
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Qingdao Univ Sci & Technol, Coll Marine Sci & Biol Engn, Shandong Prov Key Lab Biochem Engn, Qingdao 266042, Peoples R China 3.Dalian Ocean Univ, Liaoning Key Lab Marine Anim Immunol, Dalian 116023, Peoples R China 4.Dalian Ocean Univ, Liaoning Key Lab Marine Anim Immunol & Dis Contro, Dalian 116023, Peoples R China 5.Dalian Ocean Univ, Dalian Key Lab Aquat Anim Dis Prevent & Control, Dalian 116023, Peoples R China
第一作者单位	实验海洋生物学重点实验室
推荐引用方式 GB/T 7714	Wang, Xiudan,Wang, Mengqiang,Wang, Weilin,et al. Transcriptional changes of Pacific oyster Crassostrea gigas reveal essential role of calcium signal pathway in response to CO2-driven acidification[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2020,741:12.
APA	Wang, Xiudan.,Wang, Mengqiang.,Wang, Weilin.,Liu, Zhaoqun.,Xu, Jiachao.,...&Song, Linsheng.(2020).Transcriptional changes of Pacific oyster Crassostrea gigas reveal essential role of calcium signal pathway in response to CO2-driven acidification.SCIENCE OF THE TOTAL ENVIRONMENT,741,12.
MLA	Wang, Xiudan,et al."Transcriptional changes of Pacific oyster Crassostrea gigas reveal essential role of calcium signal pathway in response to CO2-driven acidification".SCIENCE OF THE TOTAL ENVIRONMENT 741(2020):12.

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