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| The Risk of Gastrointestinal Hemorrhage in Low-Dose Aspirin Users with Diabetes Mellitus: Systematic Review and Meta-Analysis | |
| Wang, Yashuo1; Wang, Wei2; Wang, Bin3; Wang, Yunyang4 | |
| 2020-08-03 | |
| 发表期刊 | GASTROENTEROLOGY RESEARCH AND PRACTICE
 |
| ISSN | 1687-6121 |
| 卷号 | 2020页码:6 |
| 摘要 | Background. Our aim was to assess the risk of gastrointestinal (GI) hemorrhage associated with diabetes among patients taking low-dose aspirin (<= 325 mg/day). Methods. A systematic search was conducted for publication in English and Chinese using term equivalents for "GI hemorrhage", "aspirin", and "diabetes mellitus" up till April 2020. Electronic databases include PUBMED, EMBASE, Cochrane Library databases, Chinese National Knowledge Infrastructure (CNKI), Wanfang Database, and VIP Database. Two independent authors searched databases and reviewed abstracts for comprehensive studies keeping adequate study quality. Data of weighted odds ratios were statistically evaluated and potential bias was checked. Results. Among 446 publications, eight case-control researches, including 1601 patients, were deemed for this meta-analysis. Patients with diabetes were associated with a higher risk of GI hemorrhage than patients without diabetes: the summary ORs were 3.10 (95% CI, 2.35-4.09). The heterogeneity of the reports was not significant (Chi(2)=3.39, P=0.85; I-2=0%). Conclusion. The meta-analysis showed that aspirin users with diabetes were more likely to have GI hemorrhage. Hence, when treating diabetics with aspirin, the increased risk of GI bleeding should be taken in consideration. |
| DOI | 10.1155/2020/9824615 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS研究方向 | Gastroenterology & Hepatology |
| WOS类目 | Gastroenterology & Hepatology |
| WOS记录号 | WOS:000562863300001 |
| 出版者 | HINDAWI LTD |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 版本 | 出版稿 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/168325 |
| 专题 | 中国科学院海洋研究所 |
| 通讯作者 | Wang, Yunyang |
| 作者单位 | 1.Qingdao Univ, Coll Life Sci, Qingdao, Shandong, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Beijing, Peoples R China 3.Qingdao Univ, Dept Med Microbiol, Med Coll, Qingdao, Shandong, Peoples R China 4.Qingdao Univ, Dept Endocrinol & Metab, Affiliated Hosp, Qingdao, Shandong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Yashuo,Wang, Wei,Wang, Bin,et al. The Risk of Gastrointestinal Hemorrhage in Low-Dose Aspirin Users with Diabetes Mellitus: Systematic Review and Meta-Analysis[J]. GASTROENTEROLOGY RESEARCH AND PRACTICE,2020,2020:6. |
| APA | Wang, Yashuo,Wang, Wei,Wang, Bin,&Wang, Yunyang.(2020).The Risk of Gastrointestinal Hemorrhage in Low-Dose Aspirin Users with Diabetes Mellitus: Systematic Review and Meta-Analysis.GASTROENTEROLOGY RESEARCH AND PRACTICE,2020,6. |
| MLA | Wang, Yashuo,et al."The Risk of Gastrointestinal Hemorrhage in Low-Dose Aspirin Users with Diabetes Mellitus: Systematic Review and Meta-Analysis".GASTROENTEROLOGY RESEARCH AND PRACTICE 2020(2020):6. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| The Risk of Gastroin（485KB） | 期刊论文 | 作者接受稿 | 限制开放 | CC BY-NC-SA | 浏览 | |
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