Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| Metabolomics Adaptation of Juvenile Pacific Abalone Haliotis discus hannai to Heat Stress | |
Xu, Fei1; Gao, Tingting1,3 ; Liu, Xiao1,2
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| 2020-04-14 | |
| Source Publication | SCIENTIFIC REPORTS
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| ISSN | 2045-2322 |
| Volume | 10Issue:1Pages:11 |
| Abstract | Temperature fluctuation is a key abiotic factor for the growth and survival of Pacific abalone Haliotis discus hannai, particularly during climate change. However, the physiological mechanism underlying the abalones' response to heat stress remains unknown. We sought to understand the metabolic adaptation mechanism of Pacific abalone to heat stress for further analyzing its heat tolerance capacity. For two groups experienced different acclimate temperature (10 degrees C and 30 degrees C for 62 days), the Pacific abalone juveniles displayed significantly different survival rates under 31 degrees C acute heat treatment. A total of 1815 and 1314 differential metabolites were identified from the 10 degrees C and 30 degrees C acclimate groups respectively, by comparing mass spectrometry data of the samples before and after heat stimulation. Heat stress led to mitochondrial failure, resulting in incomplete oxidative metabolism of amino acids and fatty acids in the mitochondria, and massive accumulation of unstable metabolic intermediates in cells. The 10 degrees C acclimated group accumulated more harmful substances after heat stimulation, provoking further stress responses and pathophysiological processes. In comparison, the 30 degrees C acclimated group showed stronger regulation capacity to produce beneficial substances for metabolic homeostasis. The findings provided insight into the heat response of marine animals, especially concerning mitochondrial metabolism. |
| DOI | 10.1038/s41598-020-63122-4 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | National Natural Science Foundation of China[41776152] ; National Natural Science Foundation of China[41676152] ; Earmarked Fund for Agriculture Seed Improvement Project of Shandong Province[2017LZGC009] ; Key Deployment Project of Centre for Ocean Mega-Research of Science, Chinese Academy of Science[COMS2019Q11] |
| WOS Research Area | Science & Technology - Other Topics |
| WOS Subject | Multidisciplinary Sciences |
| WOS ID | WOS:000562162800031 |
| Publisher | NATURE PUBLISHING GROUP |
| Citation statistics | |
| Document Type | 期刊论文 |
| Version | 出版稿 |
| Identifier | http://ir.qdio.ac.cn/handle/337002/168289 |
| Collection | 实验海洋生物学重点实验室 |
| Corresponding Author | Xu, Fei |
| Affiliation | 1.Chinese Acad Sci, Inst Oceanol, Ctr Mega Sci, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Zhejiang Ocean Univ, Key Lab Marine Fishery Equipment & Technol Zhejia, Fishery Coll, Zhoushan 316022, Peoples R China 3.Univ Chinese Acad Sci, Beijing 10049, Peoples R China |
| First Author Affilication | Institute of Oceanology, Chinese Academy of Sciences |
| Corresponding Author Affilication | Institute of Oceanology, Chinese Academy of Sciences |
| Recommended Citation GB/T 7714 | Xu, Fei,Gao, Tingting,Liu, Xiao. Metabolomics Adaptation of Juvenile Pacific Abalone Haliotis discus hannai to Heat Stress[J]. SCIENTIFIC REPORTS,2020,10(1):11. |
| APA | Xu, Fei,Gao, Tingting,&Liu, Xiao.(2020).Metabolomics Adaptation of Juvenile Pacific Abalone Haliotis discus hannai to Heat Stress.SCIENTIFIC REPORTS,10(1),11. |
| MLA | Xu, Fei,et al."Metabolomics Adaptation of Juvenile Pacific Abalone Haliotis discus hannai to Heat Stress".SCIENTIFIC REPORTS 10.1(2020):11. |
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