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Metabolomics Adaptation of Juvenile Pacific Abalone Haliotis discus hannai to Heat Stress
Xu, Fei1; Gao, Tingting1,3; Liu, Xiao1,2
2020-04-14
Source PublicationSCIENTIFIC REPORTS
ISSN2045-2322
Volume10Issue:1Pages:11
AbstractTemperature fluctuation is a key abiotic factor for the growth and survival of Pacific abalone Haliotis discus hannai, particularly during climate change. However, the physiological mechanism underlying the abalones' response to heat stress remains unknown. We sought to understand the metabolic adaptation mechanism of Pacific abalone to heat stress for further analyzing its heat tolerance capacity. For two groups experienced different acclimate temperature (10 degrees C and 30 degrees C for 62 days), the Pacific abalone juveniles displayed significantly different survival rates under 31 degrees C acute heat treatment. A total of 1815 and 1314 differential metabolites were identified from the 10 degrees C and 30 degrees C acclimate groups respectively, by comparing mass spectrometry data of the samples before and after heat stimulation. Heat stress led to mitochondrial failure, resulting in incomplete oxidative metabolism of amino acids and fatty acids in the mitochondria, and massive accumulation of unstable metabolic intermediates in cells. The 10 degrees C acclimated group accumulated more harmful substances after heat stimulation, provoking further stress responses and pathophysiological processes. In comparison, the 30 degrees C acclimated group showed stronger regulation capacity to produce beneficial substances for metabolic homeostasis. The findings provided insight into the heat response of marine animals, especially concerning mitochondrial metabolism.
DOI10.1038/s41598-020-63122-4
Indexed BySCI
Language英语
Funding ProjectNational Natural Science Foundation of China[41776152] ; National Natural Science Foundation of China[41676152] ; Earmarked Fund for Agriculture Seed Improvement Project of Shandong Province[2017LZGC009] ; Key Deployment Project of Centre for Ocean Mega-Research of Science, Chinese Academy of Science[COMS2019Q11]
WOS Research AreaScience & Technology - Other Topics
WOS SubjectMultidisciplinary Sciences
WOS IDWOS:000562162800031
PublisherNATURE PUBLISHING GROUP
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.qdio.ac.cn/handle/337002/168289
Collection实验海洋生物学重点实验室
Corresponding AuthorXu, Fei
Affiliation1.Chinese Acad Sci, Inst Oceanol, Ctr Mega Sci, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Zhejiang Ocean Univ, Key Lab Marine Fishery Equipment & Technol Zhejia, Fishery Coll, Zhoushan 316022, Peoples R China
3.Univ Chinese Acad Sci, Beijing 10049, Peoples R China
First Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Corresponding Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Xu, Fei,Gao, Tingting,Liu, Xiao. Metabolomics Adaptation of Juvenile Pacific Abalone Haliotis discus hannai to Heat Stress[J]. SCIENTIFIC REPORTS,2020,10(1):11.
APA Xu, Fei,Gao, Tingting,&Liu, Xiao.(2020).Metabolomics Adaptation of Juvenile Pacific Abalone Haliotis discus hannai to Heat Stress.SCIENTIFIC REPORTS,10(1),11.
MLA Xu, Fei,et al."Metabolomics Adaptation of Juvenile Pacific Abalone Haliotis discus hannai to Heat Stress".SCIENTIFIC REPORTS 10.1(2020):11.
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