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Cpx对迟缓爱德华氏菌毒力的影响
潘海建; 郝斌; 李杰; 李贵阳; 肖鹏; 莫照兰
2013-02-15
Source Publication海洋科学
Issue2Pages:17-21
Abstract迟缓爱德华氏菌(Edwardsiella tarda)是水产养殖动物常见病原菌。接合质粒表达系统(conjugativeplasmid expression,Cpx)是G–菌的双组分调控系统。本研究构建了迟缓爱德华氏菌LSE40的cpx基因簇缺失突变株Δcpx,检测其对蓝曼龙(Trichogaster trichopterus)的毒力。结果显示以浸泡感染,Δcpx的毒力有所降低。以肌肉注射途径感染,Δcpx的半数致死量为8.6×105cfu/mL毒力下降7.33倍。Δcpx在鱼体内的生存力显著下降(P<0.05)。这些结果表明Cpx参与了迟缓爱德华氏菌的致病作用。
Keyword迟缓爱德华氏菌(Edwardsiella Tarda)Lse40 Cpx 毒力
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/16799
Collection实验海洋生物学重点实验室
Recommended Citation
GB/T 7714
潘海建,郝斌,李杰,等. Cpx对迟缓爱德华氏菌毒力的影响[J]. 海洋科学,2013(2):17-21.
APA 潘海建,郝斌,李杰,李贵阳,肖鹏,&莫照兰.(2013).Cpx对迟缓爱德华氏菌毒力的影响.海洋科学(2),17-21.
MLA 潘海建,et al."Cpx对迟缓爱德华氏菌毒力的影响".海洋科学 .2(2013):17-21.
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