IOCAS-IR  > 实验海洋生物学重点实验室
Dimeric hexylitaconic acids from the marine-derived fungusAspergillus welwitschiaeCUGBMF180262
Han, Jiahui1,2; Yang, Na3,4; Wei, Shangzhu1; Jia, Jia5; Lin, Rui1; Li, Jiangpeng1; Bi, Hongkai5; Song, Fuhang2,6; Xu, Xiuli1
2020-07-14
Source PublicationNATURAL PRODUCT RESEARCH
ISSN1478-6419
Pages8
Corresponding AuthorSong, Fuhang(songfuhang@btbu.edu.cn) ; Xu, Xiuli(xuxl@cugb.edu.cn)
AbstractIn the course of our efforts to search new secondary metabolites from marine-derived fungi, one new hexylitaconic acid derivative, 3-(5-methoxycarbonylpentyl)-4-methylfuran-2,5-dione (1), and two dimeric analogues asperwelwinates A and B (2and3), together with ten known compounds, asperitaconic acid C (4), kotanin (5) and orlandin (6), desertorin B (7), fonsecinone A (8), aurasperone A (9), asperpyrones B and C (10 and11), aspernigrin B (12), and pyrophen (13), were isolated from a strain ofAspergillus welwitschiaeCUGBMF180262. The structures of compounds1-3were determined by detailed analysis of HRMS, and 1D/2D NMR experiments, while the absolute configurations of2and3were determined by comparison of experimental and calculated electronic circular dichroism spectra.2and3were first reported dimeric hexylitaconic acid derivatives. Compounds8,9and11showed moderate antibacterial activities againstHelicobacter pyloriwith minimum inhibitory concentration (MIC) values of 16 mu g/mL.
KeywordMarine-derivedAspergillus welwitschiae dimeric hexylitaconic acid anti-Helicobacter pylori
DOI10.1080/14786419.2020.1793152
Indexed BySCI
Language英语
Funding ProjectNational Key Research and Development Program of China[2018YFC0311002] ; National Key Research and Development Program of China[2017YFD0201203] ; National Key Research and Development Program of China[2017YFC1601300] ; National Natural Science Foundation of China[81973204]
WOS Research AreaChemistry ; Pharmacology & Pharmacy
WOS SubjectChemistry, Applied ; Chemistry, Medicinal
WOS IDWOS:000548987500001
PublisherTAYLOR & FRANCIS LTD
Citation statistics
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/167964
Collection实验海洋生物学重点实验室
Corresponding AuthorSong, Fuhang; Xu, Xiuli
Affiliation1.China Univ Geosci, Sch Ocean Sci, Beijing, Peoples R China
2.Chinese Acad Sci, Inst Microbiol, Key Lab Pathogen Microbiol & Immunol, Beijing, Peoples R China
3.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Expt Marine Biol, Qingdao, Shandong, Peoples R China
4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Shandong, Peoples R China
5.Nanjing Med Univ, Dept Modern Pathogen Biol, Jiangsu Key Lab Modern Pathogen Biol, Nanjing, Jiangsu, Peoples R China
6.Beijing Technol & Business Univ, Sch Light Ind, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Han, Jiahui,Yang, Na,Wei, Shangzhu,et al. Dimeric hexylitaconic acids from the marine-derived fungusAspergillus welwitschiaeCUGBMF180262[J]. NATURAL PRODUCT RESEARCH,2020:8.
APA Han, Jiahui.,Yang, Na.,Wei, Shangzhu.,Jia, Jia.,Lin, Rui.,...&Xu, Xiuli.(2020).Dimeric hexylitaconic acids from the marine-derived fungusAspergillus welwitschiaeCUGBMF180262.NATURAL PRODUCT RESEARCH,8.
MLA Han, Jiahui,et al."Dimeric hexylitaconic acids from the marine-derived fungusAspergillus welwitschiaeCUGBMF180262".NATURAL PRODUCT RESEARCH (2020):8.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Han, Jiahui]'s Articles
[Yang, Na]'s Articles
[Wei, Shangzhu]'s Articles
Baidu academic
Similar articles in Baidu academic
[Han, Jiahui]'s Articles
[Yang, Na]'s Articles
[Wei, Shangzhu]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Han, Jiahui]'s Articles
[Yang, Na]'s Articles
[Wei, Shangzhu]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.