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Changes in Symbiotic Microbiota and Immune Responses in Early Development Stages ofRapana venosa(Valenciennes, 1846) Provide Insights Into Immune System Development in Gastropods
Yang, Mei-Jie1,2,3,4,5; Song, Hao1,2,3,4; Yu, Zheng-Lin1,2,3,4; Hu, Zhi1,2,3,4,5; Zhou, Cong1,2,3,4,5; Wang, Xiao-Long1; Zhang, Tao1,2,3,4
2020-06-16
Source PublicationFRONTIERS IN MICROBIOLOGY
ISSN1664-302X
Volume11Pages:14
Corresponding AuthorZhang, Tao(tzhang@qdio.ac.cn)
AbstractThe symbiotic microbiota can stimulate modulation of immune system, which also can promote immune system mature in critical developmental periods. In this study, we have investigated the symbiotic microbiota inRapana venosaat five early development stages using Illumina high-throughput sequencing, and detected immune responses in larvae. Analysis of the symbiotic microbiota sequences identified that the most abundant phylum was Proteobacteria. Beta diversity analysis indicated that the structure of the symbiotic microbiota dramatically shifted in early development stages. The abundance of immune-related KEGG Orthologs (KOs) also increased in competent larval (J4, 30-day post-hatching) and postlarval after 3 days of metamorphosis (Y5, 33-day post-hatching) stages. Acid phosphatase activity decreased significantly in the Y5 stage, and alkaline phosphatase activity also at a lower level in Y5 stage, whereas lysozyme activities exhibited no remarkable change. Also, the activities of catalase and superoxide dismutase activities decreased dramatically during early development stages ofR. venosa.Dramatic changes in the symbiotic microbiota and the immune response mainly occurred in the initially hatched veliger (C1), competent larval (J4) and postlarval (Y5) stages, during which the hosts might experience substantial environmental changes or changes in physiological structure and function. These findings expand our understanding of the stage-specific symbiotic microbiota inR. venosaand the close association between immune system and symbiotic microbiota in mollusks, however, the specific relationship may need more researches are needed to investigated in the future.
KeywordRapana venosa symbiotic microbiota immune system metamorphosis early development stages
DOI10.3389/fmicb.2020.01265
Indexed BySCI
Language英语
Funding ProjectNational Key Research and Development Program of China[2019YFD0900800] ; National Natural Science Foundation of China[31572636] ; National Natural Science Foundation of China[31972814] ; Natural Science Foundation of Shandong Province[ZR2019BD003] ; China Postdoctoral Science Foundation[2019M652498] ; Major Scientific and Technological Innovation Project of Shandong Provincial Key Research and Development Program[2019JZZY020708] ; Earmarked Fund for Modern Agroindustry Technology Research System[CARS-49] ; Industry Leading Talents Project of Taishan Scholars ; `Double Hundred' Blue Industry Leader Team of Yantai ; Creative Team Project of the Laboratory for Marine Ecology and Environmental Science, Qingdao National Laboratory for Marine Science and Technology[LMEES-CTSP-2018-1]
WOS Research AreaMicrobiology
WOS SubjectMicrobiology
WOS IDWOS:000546906000001
PublisherFRONTIERS MEDIA SA
Citation statistics
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/167889
Collection海洋生态与环境科学重点实验室
Corresponding AuthorZhang, Tao
Affiliation1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao, Peoples R China
2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Sci & Technol, Qingdao, Peoples R China
3.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao, Peoples R China
4.Chinese Acad Sci, Inst Oceanol, CAS Engn Lab Marine Ranching, Qingdao, Peoples R China
5.Univ Chinese Acad Sci, Beijing, Peoples R China
First Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences;  Center for Ocean Mega-Science, Chinese Academy of Sciences
Corresponding Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences;  Center for Ocean Mega-Science, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Yang, Mei-Jie,Song, Hao,Yu, Zheng-Lin,et al. Changes in Symbiotic Microbiota and Immune Responses in Early Development Stages ofRapana venosa(Valenciennes, 1846) Provide Insights Into Immune System Development in Gastropods[J]. FRONTIERS IN MICROBIOLOGY,2020,11:14.
APA Yang, Mei-Jie.,Song, Hao.,Yu, Zheng-Lin.,Hu, Zhi.,Zhou, Cong.,...&Zhang, Tao.(2020).Changes in Symbiotic Microbiota and Immune Responses in Early Development Stages ofRapana venosa(Valenciennes, 1846) Provide Insights Into Immune System Development in Gastropods.FRONTIERS IN MICROBIOLOGY,11,14.
MLA Yang, Mei-Jie,et al."Changes in Symbiotic Microbiota and Immune Responses in Early Development Stages ofRapana venosa(Valenciennes, 1846) Provide Insights Into Immune System Development in Gastropods".FRONTIERS IN MICROBIOLOGY 11(2020):14.
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