Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| A new steroid with 7 beta,8 beta-epoxidation from the deep sea-derived fungus Aspergillus penicillioides SD-311 | |
Chi, Lu-Ping1,2 ; Yang, Sui-Qun1,3,4; Li, Xiao-Ming1,3,4; Li, Xiao-Dong1; Wang, Bin-Gui1,3,4; Li, Xin1,3,4
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| 2020-07-10 | |
| Source Publication | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
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| ISSN | 1028-6020 |
| Pages | 8 |
| Corresponding Author | Wang, Bin-Gui(wangbg@ms.qdio.ac.cn) ; Li, Xin(lixin@qdio.ac.cn) |
| Abstract | 7 beta,8 beta-epoxy-(22E,24R)-24-methylcholesta-4,22-diene-3,6-dione (1), a new steroid, along with five known analogues (2-6), was isolated from the deep sea-derived fungus,Aspergillus penicillioidesSD-311. Strikingly,1possessed a rare 7,8-epoxidation moiety. Meanwhile, this is the first time to report natural products from this fungus species. The structures were established by extensive spectroscopic analysis. The absolute configuration was determined by X-ray diffraction experiments. Compound1showed antibacterial activity againstVibrio anguillarumwith MIC value of 32.0 mu g/mL, while2displayed inhibitions againstEdwardsiella tardaandMicrococcus luteuswith MIC values both of 16 mu g/mL. [GRAPHICS] . |
| Keyword | Aspergillus penicillioides deep sea-derived fungus 7 beta,8 beta-epoxy steroid marine natural products |
| DOI | 10.1080/10286020.2020.1791096 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | Strategic Priority Research Program of Chinese Academy of Sciences[XDA22050401] ; Aoshan Scientific and Technological Innovation Project of Qingdao National Laboratory for Marine Science and Technology[2016ASKJ14] ; National Natural Science Foundation of China[31700043] |
| WOS Research Area | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| WOS Subject | Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| WOS ID | WOS:000547747800001 |
| Publisher | TAYLOR & FRANCIS LTD |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.qdio.ac.cn/handle/337002/167823 |
| Collection | 实验海洋生物学重点实验室 |
| Corresponding Author | Wang, Bin-Gui; Li, Xin |
| Affiliation | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Coll Earth & Planetary Sci, Beijing 100864, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Megasci, Qingdao 266071, Peoples R China |
| First Author Affilication | Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences |
| Corresponding Author Affilication | Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences; Center for Ocean Mega-Science, Chinese Academy of Sciences |
| Recommended Citation GB/T 7714 | Chi, Lu-Ping,Yang, Sui-Qun,Li, Xiao-Ming,et al. A new steroid with 7 beta,8 beta-epoxidation from the deep sea-derived fungus Aspergillus penicillioides SD-311[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2020:8. |
| APA | Chi, Lu-Ping,Yang, Sui-Qun,Li, Xiao-Ming,Li, Xiao-Dong,Wang, Bin-Gui,&Li, Xin.(2020).A new steroid with 7 beta,8 beta-epoxidation from the deep sea-derived fungus Aspergillus penicillioides SD-311.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,8. |
| MLA | Chi, Lu-Ping,et al."A new steroid with 7 beta,8 beta-epoxidation from the deep sea-derived fungus Aspergillus penicillioides SD-311".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2020):8. |
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| A new steroid with 7（1373KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View | |
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