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AcOH-mediated aerobic oxidative synthesis of 2-thioalkylbenzothiazoles via a three-component reaction
Li, Xiaowei1,3,4; Li, Yuxiu2; Liu, Ruihua2; Wang, Zemin2; Li, Xiangqian2; Shi, Dayong2,3,4
2020-06-25
发表期刊TETRAHEDRON LETTERS
ISSN0040-4039
卷号61期号:26页码:5
通讯作者Shi, Dayong(shidayong@sdu.edu.cn)
摘要An AcOH-mediated three-component reaction of 2-aminothiophenols, alpha,beta-unsaturated aldehydes, and thiophenols to prepare the high value-added 2-thioalkylbenzothiazoles was developed. The reaction was conducted under metal-free conditions, where oxygen served as the terminal oxidant. In addition, this strategy is tolerant of kinds of functional groups, providing efficient access to a variety of functionalized benzothiazole derivatives in moderate to good yields. What's more, this reaction has complete regioslectivity and provides a powerful method for building complex molecules. (C) 2020 Elsevier Ltd. All rights reserved.
关键词2-Thioalkylbenzothiazoles Metal-free Aerobic oxidation Multicomponent reaction
DOI10.1016/j.tetlet.2020.152054
收录类别SCI
语种英语
资助项目Shandong Provincial Natural Science Foundation for Distinguished Young Scholars[JQ201722] ; Taishan scholar Youth Project of Shandong province ; Qingdao Marine Biomedical Science and Technology Innovation Center Project[2017-CXZX01-1-1] ; Qingdao Marine Biomedical Science and Technology Innovation Center Project[2017-CXZX01-3-9] ; NSFC-Shandong Joint Fund[U1706213] ; National Natural Science Foundation of China[81803344] ; China Postdoctoral Science Foundation[2019M662374] ; China Postdoctoral Science Foundation[2019M662377] ; China Postdoctoral Science Foundation[2019M662378] ; National Program for Support of Top-notch Young Professionals ; Key research and development plan (soft science) project of Shandong province[2019RKE27018]
WOS研究方向Chemistry
WOS类目Chemistry, Organic
WOS记录号WOS:000540277100014
出版者PERGAMON-ELSEVIER SCIENCE LTD
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/167673
专题实验海洋生物学重点实验室
通讯作者Shi, Dayong
作者单位1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, 7 Nanhai Rd, Qingdao 266071, Shandong, Peoples R China
2.Shandong Univ, State Key Lab Microbial Technol, 72 Binhai Rd, Qingdao 266237, Peoples R China
3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, Qingdao 266000, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
第一作者单位中国科学院海洋研究所
推荐引用方式
GB/T 7714
Li, Xiaowei,Li, Yuxiu,Liu, Ruihua,et al. AcOH-mediated aerobic oxidative synthesis of 2-thioalkylbenzothiazoles via a three-component reaction[J]. TETRAHEDRON LETTERS,2020,61(26):5.
APA Li, Xiaowei,Li, Yuxiu,Liu, Ruihua,Wang, Zemin,Li, Xiangqian,&Shi, Dayong.(2020).AcOH-mediated aerobic oxidative synthesis of 2-thioalkylbenzothiazoles via a three-component reaction.TETRAHEDRON LETTERS,61(26),5.
MLA Li, Xiaowei,et al."AcOH-mediated aerobic oxidative synthesis of 2-thioalkylbenzothiazoles via a three-component reaction".TETRAHEDRON LETTERS 61.26(2020):5.
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