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Structural and Bioactive Studies of Halogenated Constituents from Sponges
Li, Chao1,2,3; Shi, Dayong1,2,3
2020
Source PublicationCURRENT MEDICINAL CHEMISTRY
ISSN0929-8673
Volume27Issue:14Pages:2335-2360
Corresponding AuthorShi, Dayong(shidayong@qdio.ac.cn)
AbstractMarine organisms are abundant sources of bioactive natural products. Among metabolites produced by sponges and their associated microbial communities, halogenated natural compounds accounted for an important part due to their potent biological activities. The present review updates and compiles a total of 258 halogenated organic compounds isolated in the past three decades, especially brominated derivatives derived from 31 genera of marine sponges. These compounds can be classified as the following classes: brominated polyunsaturated lipids, nitrogen compounds, brominated tyrosine derivatives and other halogenated compounds. These substances were listed together with their source organisms, structures and bioactivities. For this purpose, 84 references were consulted.
KeywordHalogenated sponges marine isolate constitutes activity
DOI10.2174/0929867325666181112092159
Indexed BySCI
Language英语
Funding ProjectNational Natural Science Foundation of China[81773586] ; National Natural Science Foundation of China[81703354] ; Key research and development project of Shandong province[2016GSF201193] ; Key research and development project of Shandong province[2016ZDJS07A13] ; Key research and development project of Shandong province[2016GSF115002] ; Key research and development project of Shandong province[2016GSF115009] ; Key Research Program of Frontier Sciences, CAS[QYZDBSSW-DQC014] ; Project of Discovery, Evaluation and Transformation of Active Natural Compounds, Strategic Biological Resources Service Network Programme of Chinese Academy of Sciences[ZSTH-026] ; Shandong Provincial Natural Science Foundation for Distinguished Young Scholars[JQ201722] ; National Program for Support of Top-notch Young Professionals ; Taishan scholar Youth Project of Shandong province
WOS Research AreaBiochemistry & Molecular Biology ; Pharmacology & Pharmacy
WOS SubjectBiochemistry & Molecular Biology ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000530214300004
PublisherBENTHAM SCIENCE PUBL LTD
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/167485
Collection实验海洋生物学重点实验室
Corresponding AuthorShi, Dayong
Affiliation1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, Qingdao 266237, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
First Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Corresponding Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Li, Chao,Shi, Dayong. Structural and Bioactive Studies of Halogenated Constituents from Sponges[J]. CURRENT MEDICINAL CHEMISTRY,2020,27(14):2335-2360.
APA Li, Chao,&Shi, Dayong.(2020).Structural and Bioactive Studies of Halogenated Constituents from Sponges.CURRENT MEDICINAL CHEMISTRY,27(14),2335-2360.
MLA Li, Chao,et al."Structural and Bioactive Studies of Halogenated Constituents from Sponges".CURRENT MEDICINAL CHEMISTRY 27.14(2020):2335-2360.
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