Effects of seawater acidification and cadmium on the antioxidant defense of flounder Paralichthys olivaceus larvae

doi:10.1016/j.scitotenv.2020.137234

	Effects of seawater acidification and cadmium on the antioxidant defense of flounder Paralichthys olivaceus larvae
	Cui, Wenting 1,3; Cao, Liang 1,2; Liu, Jinhu 1,2; Ren, Zhonghua 1,3; Zhao, Bo1 ; Dou, Shuozeng 1,2,3
	2020-05-20
发表期刊	SCIENCE OF THE TOTAL ENVIRONMENT
ISSN	0048-9697
卷号	718 页码:13
通讯作者	Dou, Shuozeng(szdou@qdio.ac.cn)
摘要	Increasing atmospheric carbon dioxide has led to a decrease in the pH of the ocean, which influences the special ion of heavy metals and consequently affects metal toxicity in marine organisms. To investigate the effects of seawater acidification and metals on the antioxidant defenses of marine fishes, the flounder Para, ichthys olivaceus, was continuously exposed to cadmium (Cd; control, 0.01 and 0.15 mg L-1) and acidified seawater (control (pH 8.10), 7.70 and 7.30) for 49 days from embryogenesis to settlement. The results demonstrated that both Cd and acidified seawater could induce oxidative stress and consequently cause lipid peroxidation (LPO) in the larvae. Antioxidants (i.e., superoxide dismutase, SOD; catalase, CAT; reduced glutathione, GSH; glutathione 5-transferase, GST; glutathione peroxidase, GPx; and glutathione reductase, GR) functioned to defend the larvae against oxidative damage. Overall, Cd induced (SOD, GST and GSH) or inhibited (CAT and GPx) the enzymatic activities or contents of all the selected antioxidants except for GR. The antioxidants responded differently to seawater acidification, depending on their interaction with the metal. Similarly, the mRNA expressions of the antioxidant-related genes were upregulated (sod, gr and gst) or downregulated (cat and gpx) in response to increasing Cd exposure. Seawater acidification did not necessarily affect all of the biomarkers; in some cases (eg, SOD and sod, GR and gr), Cd stress may have exceeded and masked the stress from seawater acidification in regulating the antioxidant defense of the larvae. The integrated biomarker response (IBR) was enhanced with increasing levels of the stressors. These findings support the hypothesis that seawater acidification not only directly affects the antioxidant defense in flounder larvae but also interacts with Cd to further regulate this defense. This study has ecological significance for assessing the long-term impacts of ocean acidification and metal pollution on the recruitment of fish populations in the wild. (C) 2020 Elsevier B.V. All rights reserved.
关键词	Early life stages Cadmium Seawater acidification Metal accumulation Oxidative stress Marine fish
DOI	10.1016/j.scitotenv.2020.137234
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China (NSFC) under the programs Science Fund for Creative Research Groups[40821004] ; National Natural Science Foundation of China (NSFC) under the programs Science Fund for Creative Research Groups[41121064] ; National Natural Science Foundation of China (NSFC) under the programs Science Fund for Creative Research Groups[41406167]
WOS研究方向	Environmental Sciences & Ecology
WOS类目	Environmental Sciences
WOS记录号	WOS:000526029000044
出版者	ELSEVIER
引用统计	被引频次：46[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/167227
专题	海洋生态与环境科学重点实验室
通讯作者	Dou, Shuozeng
作者单位	1.Chinese Acad Sci, Ctr Ocean Megasci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China
第一作者单位	中国科学院海洋大科学研究中心
通讯作者单位	中国科学院海洋大科学研究中心
推荐引用方式 GB/T 7714	Cui, Wenting,Cao, Liang,Liu, Jinhu,et al. Effects of seawater acidification and cadmium on the antioxidant defense of flounder Paralichthys olivaceus larvae[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2020,718:13.
APA	Cui, Wenting,Cao, Liang,Liu, Jinhu,Ren, Zhonghua,Zhao, Bo,&Dou, Shuozeng.(2020).Effects of seawater acidification and cadmium on the antioxidant defense of flounder Paralichthys olivaceus larvae.SCIENCE OF THE TOTAL ENVIRONMENT,718,13.
MLA	Cui, Wenting,et al."Effects of seawater acidification and cadmium on the antioxidant defense of flounder Paralichthys olivaceus larvae".SCIENCE OF THE TOTAL ENVIRONMENT 718(2020):13.

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