New 18-oxygenated polyhydroxy steroid from a South China Sea soft coral Sarcophyton sp.

doi:10.1080/14786419.2013.814053

IOCAS-IR > 实验海洋生物学重点实验室

	New 18-oxygenated polyhydroxy steroid from a South China Sea soft coral Sarcophyton sp.
	Sun, Ling-Ling 1,2; Fu, Xiu-Mei 1; Li, Xiu-Bao 3; Xing, Qian 1; Wang, Chang-Yun 1; Wang, CY
	2013-11-01
发表期刊	NATURAL PRODUCT RESEARCH
ISSN	1478-6419
卷号	27 期号:21 页码:2006-2011
文章类型	Article
摘要	One new 18-oxygenated polyhydroxy steroid, (24S)-ergostan-3,5,6,18,25-pentaol 18,25-diacetate (1), along with five known analogues (2-6), was isolated from a soft coral Sarcophyton sp. collected from the South China Sea. The structure of the new compound (1) was elucidated by 1D NMR, 2D NMR and mass spectrometry. The absolute configuration of 1 was determined by the application of the modified Mosher's method. The isolated compounds were assayed for their cytotoxic and antimicrobial activities.; One new 18-oxygenated polyhydroxy steroid, (24S)-ergostan-3,5,6,18,25-pentaol 18,25-diacetate (1), along with five known analogues (2-6), was isolated from a soft coral Sarcophyton sp. collected from the South China Sea. The structure of the new compound (1) was elucidated by 1D NMR, 2D NMR and mass spectrometry. The absolute configuration of 1 was determined by the application of the modified Mosher's method. The isolated compounds were assayed for their cytotoxic and antimicrobial activities.
关键词	Sarcophyton Sp Soft Coral Polyhydroxylated Steroids Absolute Configuration
学科领域	Chemistry ; Pharmacology & Pharmacy
DOI	10.1080/14786419.2013.814053
URL	查看原文
收录类别	SCI
语种	英语
WOS研究方向	Chemistry ; Pharmacology & Pharmacy
WOS类目	Chemistry, Applied ; Chemistry, Medicinal
WOS记录号	WOS:000327834100012
WOS关键词	INFUNDIBULIFORME
WOS标题词	Science & Technology ; Physical Sciences ; Life Sciences & Biomedicine
引用统计	被引频次：8[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/16608
专题	实验海洋生物学重点实验室
通讯作者	Wang, CY
作者单位	1.Ocean Univ China, Sch Med & Pharm, Minist Educ China, Key Lab Marine Drugs, Qingdao 266003, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 3.Chinese Acad Sci, South China Sea Inst Oceanol, Guangzhou 510000, Guangdong, Peoples R China
第一作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Sun, Ling-Ling,Fu, Xiu-Mei,Li, Xiu-Bao,et al. New 18-oxygenated polyhydroxy steroid from a South China Sea soft coral Sarcophyton sp.[J]. NATURAL PRODUCT RESEARCH,2013,27(21):2006-2011.
APA	Sun, Ling-Ling,Fu, Xiu-Mei,Li, Xiu-Bao,Xing, Qian,Wang, Chang-Yun,&Wang, CY.(2013).New 18-oxygenated polyhydroxy steroid from a South China Sea soft coral Sarcophyton sp..NATURAL PRODUCT RESEARCH,27(21),2006-2011.
MLA	Sun, Ling-Ling,et al."New 18-oxygenated polyhydroxy steroid from a South China Sea soft coral Sarcophyton sp.".NATURAL PRODUCT RESEARCH 27.21(2013):2006-2011.

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