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Cyclonerane sesquiterpenes and an isocoumarin derivative from the marine-alga-endophytic fungus Trichoderma citrinoviride A-WH-20-3
Liu, Xiang-Hong1,2,3; Hou, Xu-Liang1,3; Song, Yin-Ping1; Wang, Bin-Gui1,2; Ji, Nai-Yun1
2020-03-01
发表期刊FITOTERAPIA
ISSN0367-326X
卷号141页码:4
通讯作者Ji, Nai-Yun(nyji@yic.ac.cn)
摘要Two new cyclonerane sesquiterpenes, (10E)-isocyclonerotriol (1) and (10Z)-isocyclonerotriol (2), and one new isocoumarin derivative, trichophenol A (3), were isolated from Trichoderma citrinoviride A-WH-20-3, an endophyte from the marine red alga Laurencia okamurai. Their structures and relative configurations were assigned by spectroscopic techniques, highlighted by using Sarotti's DP4+ sheet to confirm the cyclopentane ring. The absolute configuration of 1 was established by comparison of experimental and calculated specific rotation data. Compounds 1 and 2 represent the first occurrence of ring-isomerized cycloneranes. Compound 3 is the first 3-phenylisocoumarin derivative from Trichoderma and features inhibition of several marine-derived bacteria and phytoplankton species.
关键词Trichoderma Terpene Sesquiterpene Cyclonerane Isocoumarin
DOI10.1016/j.fitote.2020.104469
收录类别SCI
语种英语
资助项目Natural Science Foundation for Distinguished Young Scholars of Shandong Province[JQ201712] ; National Natural Science Foundation of China[31670355] ; Youth Innovation Promotion Association of CAS[2013138] ; Shuangbai Plan of Yantai[2018-3] ; Taishan Scholar Project Special Funding[tsqn201909164]
WOS研究方向Pharmacology & Pharmacy
WOS类目Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000518703900012
出版者ELSEVIER
引用统计
被引频次:19[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/165835
专题实验海洋生物学重点实验室
通讯作者Ji, Nai-Yun
作者单位1.Chinese Acad Sci, Ctr Ocean Mega Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
2.Chinese Acad Sci, Lab Marine Biol & Biotechnol, Qingdao Natl Lab Marine Sci & Technol, Key Lab Expt Marine Biol,Inst Oceanol, Qingdao 266071, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
第一作者单位中国科学院海洋研究所
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Liu, Xiang-Hong,Hou, Xu-Liang,Song, Yin-Ping,et al. Cyclonerane sesquiterpenes and an isocoumarin derivative from the marine-alga-endophytic fungus Trichoderma citrinoviride A-WH-20-3[J]. FITOTERAPIA,2020,141:4.
APA Liu, Xiang-Hong,Hou, Xu-Liang,Song, Yin-Ping,Wang, Bin-Gui,&Ji, Nai-Yun.(2020).Cyclonerane sesquiterpenes and an isocoumarin derivative from the marine-alga-endophytic fungus Trichoderma citrinoviride A-WH-20-3.FITOTERAPIA,141,4.
MLA Liu, Xiang-Hong,et al."Cyclonerane sesquiterpenes and an isocoumarin derivative from the marine-alga-endophytic fungus Trichoderma citrinoviride A-WH-20-3".FITOTERAPIA 141(2020):4.
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