Cyclonerane sesquiterpenes and an isocoumarin derivative from the marine-alga-endophytic fungus Trichoderma citrinoviride A-WH-20-3

doi:10.1016/j.fitote.2020.104469

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	Cyclonerane sesquiterpenes and an isocoumarin derivative from the marine-alga-endophytic fungus Trichoderma citrinoviride A-WH-20-3
	Liu, Xiang-Hong 1,2,3; Hou, Xu-Liang 1,3; Song, Yin-Ping 1; Wang, Bin-Gui1,2 ; Ji, Nai-Yun 1
	2020-03-01
Source Publication	FITOTERAPIA
ISSN	0367-326X
Volume	141 Pages:4
Corresponding Author	Ji, Nai-Yun(nyji@yic.ac.cn)
Abstract	Two new cyclonerane sesquiterpenes, (10E)-isocyclonerotriol (1) and (10Z)-isocyclonerotriol (2), and one new isocoumarin derivative, trichophenol A (3), were isolated from Trichoderma citrinoviride A-WH-20-3, an endophyte from the marine red alga Laurencia okamurai. Their structures and relative configurations were assigned by spectroscopic techniques, highlighted by using Sarotti's DP4+ sheet to confirm the cyclopentane ring. The absolute configuration of 1 was established by comparison of experimental and calculated specific rotation data. Compounds 1 and 2 represent the first occurrence of ring-isomerized cycloneranes. Compound 3 is the first 3-phenylisocoumarin derivative from Trichoderma and features inhibition of several marine-derived bacteria and phytoplankton species.
Keyword	Trichoderma Terpene Sesquiterpene Cyclonerane Isocoumarin
DOI	10.1016/j.fitote.2020.104469
Indexed By	SCI
Language	英语
Funding Project	Natural Science Foundation for Distinguished Young Scholars of Shandong Province[JQ201712] ; National Natural Science Foundation of China[31670355] ; Youth Innovation Promotion Association of CAS[2013138] ; Shuangbai Plan of Yantai[2018-3] ; Taishan Scholar Project Special Funding[tsqn201909164]
WOS Research Area	Pharmacology & Pharmacy
WOS Subject	Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS ID	WOS:000518703900012
Publisher	ELSEVIER
Citation statistics	Cited Times:1[WOS] [WOS Record] [Related Records in WOS]
Document Type	期刊论文
Identifier	http://ir.qdio.ac.cn/handle/337002/165835
Collection	实验海洋生物学重点实验室
Corresponding Author	Ji, Nai-Yun
Affiliation	1.Chinese Acad Sci, Ctr Ocean Mega Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Lab Marine Biol & Biotechnol, Qingdao Natl Lab Marine Sci & Technol, Key Lab Expt Marine Biol,Inst Oceanol, Qingdao 266071, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
First Author Affilication	Institute of Oceanology, Chinese Academy of Sciences
Recommended Citation GB/T 7714	Liu, Xiang-Hong,Hou, Xu-Liang,Song, Yin-Ping,et al. Cyclonerane sesquiterpenes and an isocoumarin derivative from the marine-alga-endophytic fungus Trichoderma citrinoviride A-WH-20-3[J]. FITOTERAPIA,2020,141:4.
APA	Liu, Xiang-Hong,Hou, Xu-Liang,Song, Yin-Ping,Wang, Bin-Gui,&Ji, Nai-Yun.(2020).Cyclonerane sesquiterpenes and an isocoumarin derivative from the marine-alga-endophytic fungus Trichoderma citrinoviride A-WH-20-3.FITOTERAPIA,141,4.
MLA	Liu, Xiang-Hong,et al."Cyclonerane sesquiterpenes and an isocoumarin derivative from the marine-alga-endophytic fungus Trichoderma citrinoviride A-WH-20-3".FITOTERAPIA 141(2020):4.

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