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Antimicrobial Chitosan Conjugates: Current Synthetic Strategies and Potential Applications
Qin, Yukun1,2; Li, Pengcheng1,2
2020-01-02
发表期刊INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
卷号21期号:2页码:19
通讯作者Qin, Yukun(ykqin@qdio.ac.cn) ; Li, Pengcheng(pcli@qdio.ac.cn)
摘要As a natural polysaccharide, chitosan possesses good biocompatibility, biodegradability and biosafety. Its hydroxyl and amino groups make it an ideal carrier material in the construction of polymer-drug conjugates. In recent years, various synthetic strategies have been used to couple chitosan with active substances to obtain conjugates with diverse structures and unique functions. In particular, chitosan conjugates with antimicrobial activity have shown great application prospects in the fields of medicine, food, and agriculture in recent years. Hence, we will place substantial emphasis on the synthetic approaches for preparing chitosan conjugates and their antimicrobial applications, which are not well summarized. Meanwhile, the challenges, limitations, and prospects of antimicrobial chitosan conjugates are described and discussed.
关键词chitosan conjugates synthetic approach antimicrobial activity applications
DOI10.3390/ijms21020499
收录类别SCI
语种英语
资助项目National Key R&D Program of China[2018YFC0311305] ; National Key R&D Program of China[2019YFD0900705] ; Key Research and Development Program of Shandong Province[2018GHY115017] ; Key Research and Development Program of Shandong Province[2018GHY115008] ; Key Research and Development Program of Shandong Province[2019GHY112015] ; Qingdao Applied Basic Research Project[19-6-2-34-cg] ; Science and technology program of Nantong[MS120170234]
WOS研究方向Biochemistry & Molecular Biology ; Chemistry
WOS类目Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS记录号WOS:000515380000129
出版者MDPI
引用统计
被引频次:61[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/165524
专题实验海洋生物学重点实验室
通讯作者Qin, Yukun; Li, Pengcheng
作者单位1.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Pilot Natl Lab Marine Sci & Technol Qingdao, Lab Marine Drugs & Bioprod, 1 Wenhai Rd, Qingdao 266237, Peoples R China
第一作者单位中国科学院海洋研究所
通讯作者单位中国科学院海洋研究所
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GB/T 7714
Qin, Yukun,Li, Pengcheng. Antimicrobial Chitosan Conjugates: Current Synthetic Strategies and Potential Applications[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2020,21(2):19.
APA Qin, Yukun,&Li, Pengcheng.(2020).Antimicrobial Chitosan Conjugates: Current Synthetic Strategies and Potential Applications.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,21(2),19.
MLA Qin, Yukun,et al."Antimicrobial Chitosan Conjugates: Current Synthetic Strategies and Potential Applications".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 21.2(2020):19.
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