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Antimicrobial Chitosan Conjugates: Current Synthetic Strategies and Potential Applications
Qin, Yukun1,2; Li, Pengcheng1,2
2020-01-02
Source PublicationINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume21Issue:2Pages:19
Corresponding AuthorQin, Yukun(ykqin@qdio.ac.cn) ; Li, Pengcheng(pcli@qdio.ac.cn)
AbstractAs a natural polysaccharide, chitosan possesses good biocompatibility, biodegradability and biosafety. Its hydroxyl and amino groups make it an ideal carrier material in the construction of polymer-drug conjugates. In recent years, various synthetic strategies have been used to couple chitosan with active substances to obtain conjugates with diverse structures and unique functions. In particular, chitosan conjugates with antimicrobial activity have shown great application prospects in the fields of medicine, food, and agriculture in recent years. Hence, we will place substantial emphasis on the synthetic approaches for preparing chitosan conjugates and their antimicrobial applications, which are not well summarized. Meanwhile, the challenges, limitations, and prospects of antimicrobial chitosan conjugates are described and discussed.
Keywordchitosan conjugates synthetic approach antimicrobial activity applications
DOI10.3390/ijms21020499
Indexed BySCI
Language英语
Funding ProjectNational Key R&D Program of China[2018YFC0311305] ; National Key R&D Program of China[2019YFD0900705] ; Key Research and Development Program of Shandong Province[2018GHY115017] ; Key Research and Development Program of Shandong Province[2018GHY115008] ; Key Research and Development Program of Shandong Province[2019GHY112015] ; Qingdao Applied Basic Research Project[19-6-2-34-cg] ; Science and technology program of Nantong[MS120170234]
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS SubjectBiochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS IDWOS:000515380000129
PublisherMDPI
Citation statistics
Cited Times:6[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/165524
Collection实验海洋生物学重点实验室
Corresponding AuthorQin, Yukun; Li, Pengcheng
Affiliation1.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Pilot Natl Lab Marine Sci & Technol Qingdao, Lab Marine Drugs & Bioprod, 1 Wenhai Rd, Qingdao 266237, Peoples R China
First Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Corresponding Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Qin, Yukun,Li, Pengcheng. Antimicrobial Chitosan Conjugates: Current Synthetic Strategies and Potential Applications[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2020,21(2):19.
APA Qin, Yukun,&Li, Pengcheng.(2020).Antimicrobial Chitosan Conjugates: Current Synthetic Strategies and Potential Applications.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,21(2),19.
MLA Qin, Yukun,et al."Antimicrobial Chitosan Conjugates: Current Synthetic Strategies and Potential Applications".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 21.2(2020):19.
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