Biological and chemical diversity of cytotoxin-producing symbiotic marine fungi in intertidal zone of Dalian

doi:10.1007/s11434-012-5442-2

IOCAS-IR > 实验海洋生物学重点实验室

	Biological and chemical diversity of cytotoxin-producing symbiotic marine fungi in intertidal zone of Dalian
	Zhang Yi 1,2,3; Mu Jun 2; Feng Yan 2; Li HeNan 2; Dong XueWei 2; Zhang, Y
	2013-07-01
发表期刊	CHINESE SCIENCE BULLETIN
ISSN	1001-6538
卷号	58 期号:19 页码:2290-2297
文章类型	Article
摘要	In this study, the biological and chemical diversity of 8 symbiotic marine fungal strains, with strong cytotoxicity against brine shrimp larvae, were investigated by nucleotide sequencing, morphology and cluster analysis of HPTLC fingerprint. These strains were identified by ITS rDNA sequencing, phylogenic analysis, and morphology to be Hypocrea lixii, Chaetomium globosum, Aspergillus fumigatus, Asp. clavatus and Alternaria sp. Their differences in secondary metabolites were shown by cluster analysis of digitalized colors of HPTLC spots, a newly developed method, which produced a similar dendrogram with that of ITS cluster analysis. Furthermore, this method can fully display intraspecific differences and even the remarkable difference in Aspergillus strains which goes beyond the boundary between genera. Their biological-chemical diversity may be the basis of their potent cytotoxicity and implies their potential in producing diversified antitumor or pesticidal constituents.; In this study, the biological and chemical diversity of 8 symbiotic marine fungal strains, with strong cytotoxicity against brine shrimp larvae, were investigated by nucleotide sequencing, morphology and cluster analysis of HPTLC fingerprint. These strains were identified by ITS rDNA sequencing, phylogenic analysis, and morphology to be Hypocrea lixii, Chaetomium globosum, Aspergillus fumigatus, Asp. clavatus and Alternaria sp. Their differences in secondary metabolites were shown by cluster analysis of digitalized colors of HPTLC spots, a newly developed method, which produced a similar dendrogram with that of ITS cluster analysis. Furthermore, this method can fully display intraspecific differences and even the remarkable difference in Aspergillus strains which goes beyond the boundary between genera. Their biological-chemical diversity may be the basis of their potent cytotoxicity and implies their potential in producing diversified antitumor or pesticidal constituents.
关键词	Symbiotic Marine Fungi Cytotoxicity Diversity Rdna Sequencing Morphology Fingerprint
学科领域	Science & Technology - Other Topics
DOI	10.1007/s11434-012-5442-2
URL	查看原文
收录类别	SCI
语种	英语
WOS研究方向	Science & Technology - Other Topics
WOS类目	Multidisciplinary Sciences
WOS记录号	WOS:000321952900005
WOS关键词	CHAETOMIUM-GLOBOSUM ; ENDOPHYTIC FUNGUS ; NATURAL-PRODUCTS ; METABOLITES ; ASPERGILLUS ; CHAETOMUGILINS ; BIOASSAY
WOS标题词	Science & Technology
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/16533
专题	实验海洋生物学重点实验室
通讯作者	Zhang, Y
作者单位	1.Dalian Univ Technol, Sch Life Sci & Biotechnol, Dalian 116024, Peoples R China 2.Dalian Jiaotong Univ, Sch Environm & Chem Engn, Dalian 116028, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
第一作者单位	实验海洋生物学重点实验室
推荐引用方式 GB/T 7714	Zhang Yi,Mu Jun,Feng Yan,et al. Biological and chemical diversity of cytotoxin-producing symbiotic marine fungi in intertidal zone of Dalian[J]. CHINESE SCIENCE BULLETIN,2013,58(19):2290-2297.
APA	Zhang Yi,Mu Jun,Feng Yan,Li HeNan,Dong XueWei,&Zhang, Y.(2013).Biological and chemical diversity of cytotoxin-producing symbiotic marine fungi in intertidal zone of Dalian.CHINESE SCIENCE BULLETIN,58(19),2290-2297.
MLA	Zhang Yi,et al."Biological and chemical diversity of cytotoxin-producing symbiotic marine fungi in intertidal zone of Dalian".CHINESE SCIENCE BULLETIN 58.19(2013):2290-2297.

条目包含的文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
Biological and chemi（715KB）			限制开放	CC BY-NC-SA	浏览