Urceolatin, a structurally unique bromophenol from Polysiphonia urceolata

doi:10.1021/ol800230t

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	Urceolatin, a structurally unique bromophenol from Polysiphonia urceolata
	Li, Ke 1,2; Li, Xiao-Ming 1; Ji, Nai-Yun 1,2; Gloer, James B.3; Wang, Bin-Gui1 ; Li, XM, Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Nanhai Rd 7, Qingdao 266071, Peoples R China
	2008-04-03
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	10 期号:7 页码:1429-1432
文章类型	Article
摘要	6-Bromo-1-(3-bromo-4,5-dihydroxybenzyl)phenanthro[4,5-bcd]furan-2,3,5-triol (urceolatin, 1), a highly oxygenated bromophenol containing an unprecedented naturally occurring benzylphenanthro[4,5-bcd]furan unit, was isolated from the marine red alga Polysiphonia urceolata. Its structure was established on the basis of extensive spectroscopic analysis. Compound 1 displayed significant DPPH radical-scavenging activity with an IC(50) value of 7.9 mu M, which is 10-fold more potent than that of the positive control, butylated hydroxytoluene.; 6-Bromo-1-(3-bromo-4,5-dihydroxybenzyl)phenanthro[4,5-bcd]furan-2,3,5-triol (urceolatin, 1), a highly oxygenated bromophenol containing an unprecedented naturally occurring benzylphenanthro[4,5-bcd]furan unit, was isolated from the marine red alga Polysiphonia urceolata. Its structure was established on the basis of extensive spectroscopic analysis. Compound 1 displayed significant DPPH radical-scavenging activity with an IC50 value of 7.9 mu M, which is 10-fold more potent than that of the positive control, butylated hydroxytoluene.
关键词	Radical-scavenging Activity Alga Laurencia-decumbens Red Alga Bletilla-striata Odonthalia Corymbifera Sesquiterpenes Rhodomelaceae
学科领域	Chemistry, Organic
DOI	10.1021/ol800230t
URL	查看原文
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000254489900027
引用统计	被引频次：27[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/1635
专题	实验海洋生物学重点实验室
通讯作者	Li, XM, Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Nanhai Rd 7, Qingdao 266071, Peoples R China
作者单位	1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 3.Univ Iowa, Dept Chem, Iowa City, IA 52242 USA
第一作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Li, Ke,Li, Xiao-Ming,Ji, Nai-Yun,et al. Urceolatin, a structurally unique bromophenol from Polysiphonia urceolata[J]. ORGANIC LETTERS,2008,10(7):1429-1432.
APA	Li, Ke,Li, Xiao-Ming,Ji, Nai-Yun,Gloer, James B.,Wang, Bin-Gui,&Li, XM, Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Nanhai Rd 7, Qingdao 266071, Peoples R China.(2008).Urceolatin, a structurally unique bromophenol from Polysiphonia urceolata.ORGANIC LETTERS,10(7),1429-1432.
MLA	Li, Ke,et al."Urceolatin, a structurally unique bromophenol from Polysiphonia urceolata".ORGANIC LETTERS 10.7(2008):1429-1432.

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