Aflatoxin B1 (AFB1) induced dysregulation of intestinal microbiota and damage of antioxidant system in pacific white shrimp (Litopenaeus vannamei)

doi:10.1016/j.aquaculture.2018.06.065

IOCAS-IR > 实验海洋生物学重点实验室

	Aflatoxin B1 (AFB1) induced dysregulation of intestinal microbiota and damage of antioxidant system in pacific white shrimp (Litopenaeus vannamei)
	Wang, Yilong 1,2,3; Wang, Baojie 1,2; Liu, Mei 1,2; Jiang, Keyong 1,2; Wang, Mengqiang1,2 ; Wang, Lei 1,2
	2018-10-01
发表期刊	AQUACULTURE
ISSN	0044-8486
卷号	495 页码:940-947
通讯作者	Wang, Mengqiang(wangmengqiang@qdio.ac.cn) ; Wang, Lei(wanglei@qdio.ac.cn)
摘要	Aflatoxins, especially aflatoxin B1 (AFB1), exert a substantial impact on the shrimp farming production, inducing disease with a gradual decline of reared shrimp stock quality and profitability, thus causing a significant problem in aquaculture systems. In order to investigate the influence of AFB1 on intestinal health and antioxidant system, we monitored the dynamic change of intestinal microbiota of pacific white shrimp (Litopenaeus vannamei) at 3-, 6-, 12-, 18-, 24-and 30-d after AFB1 challenge. Meanwhile, we determined the activities of several important antioxidant enzymes including superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX) and the content of malondialdehyde (MDA) in the intestines and hepatopancreas. The results showed that, the types of intestinal microbiota in the control group are more abundant than the experimental group both at the phyla level and genera level. At the phyla level, the relative abundance of Proteobacteria and Firmicutes in the experimental group increased obviously with the culture days extension, while the relative abundance of Bacteroidetes decreased. At the genera level, the relative abundance of Vibrio and Photobacterium in the experimental group increased evidently, while the relative abundance of Flavobacterium_sp_M and Tenacibaculum decreased. The CAT, SOD and GPX activities of intestinal and hepatopancreas were significantly higher in the experimental group than in the control group, and showed a tendency to increase first and then decrease as a whole while the content of MDA changes on the contrary. All above findings suggested that AFB1 could induce dysregulation of intestinal microbiota and damage of antioxidant system in pacific white shrimp (Litopenaeus vannamei).
关键词	Pacific white shrimp Aflatoxin B1 Intestinal microbiota Antioxidant system
DOI	10.1016/j.aquaculture.2018.06.065
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China-Joint Fund of Shandong People's Government[U1706209] ; Chinese Academy of Sciences STS Regional Center Project (Fujian Province) ; National Natural Science Foundation of China-Joint Fund of Shandong People's Government[U1706209] ; Chinese Academy of Sciences STS Regional Center Project (Fujian Province)
WOS研究方向	Fisheries ; Marine & Freshwater Biology
WOS类目	Fisheries ; Marine & Freshwater Biology
WOS记录号	WOS:000439123500114
出版者	ELSEVIER SCIENCE BV
引用统计	被引频次：60[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/163499
专题	实验海洋生物学重点实验室
通讯作者	Wang, Mengqiang; Wang, Lei
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Wang, Yilong,Wang, Baojie,Liu, Mei,et al. Aflatoxin B1 (AFB1) induced dysregulation of intestinal microbiota and damage of antioxidant system in pacific white shrimp (Litopenaeus vannamei)[J]. AQUACULTURE,2018,495:940-947.
APA	Wang, Yilong,Wang, Baojie,Liu, Mei,Jiang, Keyong,Wang, Mengqiang,&Wang, Lei.(2018).Aflatoxin B1 (AFB1) induced dysregulation of intestinal microbiota and damage of antioxidant system in pacific white shrimp (Litopenaeus vannamei).AQUACULTURE,495,940-947.
MLA	Wang, Yilong,et al."Aflatoxin B1 (AFB1) induced dysregulation of intestinal microbiota and damage of antioxidant system in pacific white shrimp (Litopenaeus vannamei)".AQUACULTURE 495(2018):940-947.