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Aflatoxin B1 (AFB1) induced dysregulation of intestinal microbiota and damage of antioxidant system in pacific white shrimp (Litopenaeus vannamei)
Wang, Yilong1,2,3; Wang, Baojie1,2; Liu, Mei1,2; Jiang, Keyong1,2; Wang, Mengqiang1,2; Wang, Lei1,2
2018-10-01
Source PublicationAQUACULTURE
ISSN0044-8486
Volume495Pages:940-947
Corresponding AuthorWang, Mengqiang(wangmengqiang@qdio.ac.cn) ; Wang, Lei(wanglei@qdio.ac.cn)
AbstractAflatoxins, especially aflatoxin B1 (AFB1), exert a substantial impact on the shrimp farming production, inducing disease with a gradual decline of reared shrimp stock quality and profitability, thus causing a significant problem in aquaculture systems. In order to investigate the influence of AFB1 on intestinal health and antioxidant system, we monitored the dynamic change of intestinal microbiota of pacific white shrimp (Litopenaeus vannamei) at 3-, 6-, 12-, 18-, 24-and 30-d after AFB1 challenge. Meanwhile, we determined the activities of several important antioxidant enzymes including superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX) and the content of malondialdehyde (MDA) in the intestines and hepatopancreas. The results showed that, the types of intestinal microbiota in the control group are more abundant than the experimental group both at the phyla level and genera level. At the phyla level, the relative abundance of Proteobacteria and Firmicutes in the experimental group increased obviously with the culture days extension, while the relative abundance of Bacteroidetes decreased. At the genera level, the relative abundance of Vibrio and Photobacterium in the experimental group increased evidently, while the relative abundance of Flavobacterium_sp_M and Tenacibaculum decreased. The CAT, SOD and GPX activities of intestinal and hepatopancreas were significantly higher in the experimental group than in the control group, and showed a tendency to increase first and then decrease as a whole while the content of MDA changes on the contrary. All above findings suggested that AFB1 could induce dysregulation of intestinal microbiota and damage of antioxidant system in pacific white shrimp (Litopenaeus vannamei).
KeywordPacific white shrimp Aflatoxin B1 Intestinal microbiota Antioxidant system
DOI10.1016/j.aquaculture.2018.06.065
Indexed BySCI
Language英语
Funding ProjectNational Natural Science Foundation of China-Joint Fund of Shandong People's Government[U1706209] ; Chinese Academy of Sciences STS Regional Center Project (Fujian Province)
WOS Research AreaFisheries ; Marine & Freshwater Biology
WOS SubjectFisheries ; Marine & Freshwater Biology
WOS IDWOS:000439123500114
PublisherELSEVIER SCIENCE BV
Citation statistics
Cited Times:10[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/163499
Collection实验海洋生物学重点实验室
Corresponding AuthorWang, Mengqiang; Wang, Lei
Affiliation1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
First Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Corresponding Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Wang, Yilong,Wang, Baojie,Liu, Mei,et al. Aflatoxin B1 (AFB1) induced dysregulation of intestinal microbiota and damage of antioxidant system in pacific white shrimp (Litopenaeus vannamei)[J]. AQUACULTURE,2018,495:940-947.
APA Wang, Yilong,Wang, Baojie,Liu, Mei,Jiang, Keyong,Wang, Mengqiang,&Wang, Lei.(2018).Aflatoxin B1 (AFB1) induced dysregulation of intestinal microbiota and damage of antioxidant system in pacific white shrimp (Litopenaeus vannamei).AQUACULTURE,495,940-947.
MLA Wang, Yilong,et al."Aflatoxin B1 (AFB1) induced dysregulation of intestinal microbiota and damage of antioxidant system in pacific white shrimp (Litopenaeus vannamei)".AQUACULTURE 495(2018):940-947.
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