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Comparative transcriptomic analysis illuminates the host-symbiont interactions in the deep-sea mussel Bathymodiolus platifrons
Wang, Hao1,3; Zhang, Huan1,3; Wang, Minxiao2,3; Chen, Hao1,3; Lian, Chao1,3; Li, Chaolun1,2,3,4
2019-09-01
Source PublicationDEEP-SEA RESEARCH PART I-OCEANOGRAPHIC RESEARCH PAPERS
ISSN0967-0637
Volume151Pages:11
Corresponding AuthorLi, Chaolun(Icl@qdio.ac.cri)
AbstractBathymodiolus platifrons adapted the chemosynthetic ecosystems, both cold seeps and hydrothermal vents, by harbouring gill symbionts. To survive these extreme and volatile ecological niches, the host mussel must be able to strictly regulate the symbionts in response to the environmental fluctuations. However, despite the research efforts, the molecular mechanisms governing host-symbiont interaction in deep-sea mussels are still largely unknown. Here, using the model deep-sea mussel Bathymodiolus plantiforns, we profiled the transcriptomic dynamic of the mussel gill during the loss and re-contact with symbionts with RNA-seq technology. The analysis of DEGs between untreated and symbiont loss samples revealed that metabolic and cellular organizational changes in the gill were associated with increased ribosomal activities, ubiquitin-proteasome systems, and autophagy. Meanwhile, the DE immune genes suggest that the host recognizes and interacts with endosymbionts through the pattern recognizing receptors, especially the Toll-like receptors. In addition, the DEGs between symbionts treated and environmental bacteria treated samples shed light on the mechanism of symbiont recognition. The symbionts treatment not only partially reversed the transcriptomic changes caused by symbiont-loss, but also suppressed host immune system which might facilitate the symbionts' entrance and survival in the host bacteriocytes. All together, these results suggest that the host-symbiont system in B. platifrons is tightly regulated but also with plasticity to fit environmental fluctuations.
KeywordSymbiosis RNA-Seq Comparative transcriptomic Bathymodiolin Deep-sea Adaptation
DOI10.1016/j.dsr.2019.103082
Indexed BySCI
Language英语
Funding ProjectNational Key R&D Program of China[2018YFC0310800] ; Scientific and Technological Innovation Project from Qingdao National Laboratory for Marine Science and Technology[2016ASKJ14] ; Senior User Project of RV KEXUE[KEXUE2016G06]
WOS Research AreaOceanography
WOS SubjectOceanography
WOS IDWOS:000488141500007
PublisherPERGAMON-ELSEVIER SCIENCE LTD
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/163239
Collection深海极端环境与生命过程研究中心
Corresponding AuthorLi, Chaolun
Affiliation1.Chinese Acad Sci, Inst Oceanol, Ctr Deep Sea Res, Qingdao, Shandong, Peoples R China
2.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Shandong, Peoples R China
3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao, Shandong, Peoples R China
4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao, Shandong, Peoples R China
First Author AffilicationChinese Acad Sci, Inst Oceanol, Ctr Deep Sea Res
Corresponding Author AffilicationChinese Acad Sci, Inst Oceanol, Ctr Deep Sea Res;  Institute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Wang, Hao,Zhang, Huan,Wang, Minxiao,et al. Comparative transcriptomic analysis illuminates the host-symbiont interactions in the deep-sea mussel Bathymodiolus platifrons[J]. DEEP-SEA RESEARCH PART I-OCEANOGRAPHIC RESEARCH PAPERS,2019,151:11.
APA Wang, Hao,Zhang, Huan,Wang, Minxiao,Chen, Hao,Lian, Chao,&Li, Chaolun.(2019).Comparative transcriptomic analysis illuminates the host-symbiont interactions in the deep-sea mussel Bathymodiolus platifrons.DEEP-SEA RESEARCH PART I-OCEANOGRAPHIC RESEARCH PAPERS,151,11.
MLA Wang, Hao,et al."Comparative transcriptomic analysis illuminates the host-symbiont interactions in the deep-sea mussel Bathymodiolus platifrons".DEEP-SEA RESEARCH PART I-OCEANOGRAPHIC RESEARCH PAPERS 151(2019):11.
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