IOCAS-IR  > 实验海洋生物学重点实验室
Ligand- and Additive-Free 2-Position-Selective Trifluoromethylation of Heteroarenes Under Ambient Conditions
Shi, Xiaolin1,2,3; Li, Xiaowei1,2,3; Li, Xiangqian4; Shi, Dayong4
2019-09-06
Source PublicationFRONTIERS IN CHEMISTRY
ISSN2296-2646
Volume7Pages:10
Corresponding AuthorLi, Xiangqian(xqli@qdio.ac.cn) ; Shi, Dayong(shidayong@sdu.edu.cn)
AbstractA highly selective copper-catalyzed trifluoromethylation of indoles is reported with the assistance of a removable directing group. This protocol provides an easy and rapid method to various 2-position-selective trifluoromethylated heteroarenes including indoles, pyrroles, benzofuran, and acetanilide. What is more, the reaction takes place at ambient conditions without any external ligand or additive.
KeywordC-H functionalization trifluoromethylation indoles copper radical reaction
DOI10.3389/fchem.2019.00613
Indexed BySCI
Language英语
Funding ProjectNational Natural Science Foundation of China[81773586] ; National Natural Science Foundation of China[81703354] ; Key research and development project of Shandong province[2016GSF201193] ; Key research and development project of Shandong province[2016ZDJS07A13] ; Key research and development project of Shandong province[2016GSF115002] ; Key research and development project of Shandong province[2016GSF115009] ; CAS[QYZDB-SSW-DQC014] ; Project of Discovery, Evaluation and Transformation of Active Natural Compounds ; Chinese Academy of Sciences[ZSTH-026] ; Shandong Provincial Natural Science Foundation for Distinguished Young Scholars[JQ201722] ; National Program for Support of Top-notch Young Professionals ; Taishan scholar Youth Project of Shandong province
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000484497100001
PublisherFRONTIERS MEDIA SA
Citation statistics
Document Type期刊论文
Identifierhttp://ir.qdio.ac.cn/handle/337002/162691
Collection实验海洋生物学重点实验室
Corresponding AuthorLi, Xiangqian; Shi, Dayong
Affiliation1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Shandong, Peoples R China
2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, Qingdao, Shandong, Peoples R China
3.Univ Chinese Acad Sci, Beijing, Peoples R China
4.Shandong Univ, State Key Lab Microbial Technol, Qingdao, Shandong, Peoples R China
First Author AffilicationInstitute of Oceanology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Shi, Xiaolin,Li, Xiaowei,Li, Xiangqian,et al. Ligand- and Additive-Free 2-Position-Selective Trifluoromethylation of Heteroarenes Under Ambient Conditions[J]. FRONTIERS IN CHEMISTRY,2019,7:10.
APA Shi, Xiaolin,Li, Xiaowei,Li, Xiangqian,&Shi, Dayong.(2019).Ligand- and Additive-Free 2-Position-Selective Trifluoromethylation of Heteroarenes Under Ambient Conditions.FRONTIERS IN CHEMISTRY,7,10.
MLA Shi, Xiaolin,et al."Ligand- and Additive-Free 2-Position-Selective Trifluoromethylation of Heteroarenes Under Ambient Conditions".FRONTIERS IN CHEMISTRY 7(2019):10.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Shi, Xiaolin]'s Articles
[Li, Xiaowei]'s Articles
[Li, Xiangqian]'s Articles
Baidu academic
Similar articles in Baidu academic
[Shi, Xiaolin]'s Articles
[Li, Xiaowei]'s Articles
[Li, Xiangqian]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Shi, Xiaolin]'s Articles
[Li, Xiaowei]'s Articles
[Li, Xiangqian]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.